Registry for patients undergoing MitraClip® procedure for mitral regurgitation

MitraClip® Registry - an Observational Study of Percutaneous Mitral Valve Repair Using the MitraClip® System

Heinrich-Heine University, Duesseldorf · NCT02033811

This study collects information from patients with severe mitral regurgitation who are treated with the MitraClip® procedure to see how well it works and how safe it is for them.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorHeinrich-Heine University, Duesseldorf (other)
Locations1 site (Düsseldorf)
Trial IDNCT02033811 on ClinicalTrials.gov

What this trial studies

This registry collects clinical data from patients with severe mitral regurgitation who are treated with the MitraClip® system, a minimally invasive procedure for mitral valve repair. The aim is to systematically assess patient characteristics and outcomes following percutaneous mitral valve repair (PMVR). By gathering this information, the registry seeks to enhance understanding of the procedure's effectiveness and safety in high-risk patients. It is an observational study, meaning it will monitor real-world outcomes without altering the treatment process.

Who should consider this trial

Good fit: Ideal candidates are adults with severe mitral regurgitation who are undergoing PMVR with the MitraClip® system.

Not a fit: Patients under 18 years old or those deemed unlikely to benefit from the procedure by the heart team will not receive benefit from this study.

Why it matters

Potential benefit: If successful, this registry could improve treatment strategies and outcomes for patients with severe mitral regurgitation.

How similar studies have performed: Other studies on percutaneous mitral valve repair have shown promising results, indicating that this approach is gaining acceptance in clinical practice.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* severe mitral regurgitation
* percutaneous mitral valve repair (PMVR) with the MitraClip® system

Exclusion Criteria:

* \< 18 years
* Patients considered by the heart team to be unlikely to receive meaningful or durable clinical benefit from the procedure

Where this trial is running

Düsseldorf

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Mitral Regurgitation, mitral regurgitation, MitraClip system, percutaneous mitral valve repair

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.