Registry for patients undergoing esophageal cancer screening

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, prospective, observational study aims to collect data on patients undergoing screening for Barrett Esophagus (BE) and Esophageal Adenocarcinoma (EAC) using the EsoGuard test and EsoCheck device. The study will gather information on patient demographics, medical history, risk factors, and clinical management following the screening. Data will be recorded in an electronic system to assess the effectiveness and patient tolerance of the EsoCheck procedure and the subsequent diagnostic results. The goal is to improve understanding of BE and EAC management based on real-world clinical practices.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Individuals in whom a healthcare provider has made the independent clinical decision to screen for BE/EAC (based on assessment of elevated disease risk) using EsoGuard for analysis of cell samples collected with EsoCheck
2. Provided written informed consent for prospective registry participation/data collection

Exclusion Criteria:

1. Inability to provide written informed consent
2. Subjects who fall outside the eligible population defined by the EsoCheck device Instructions For Use (IFU)

Where it's running

• Lucid Dx
  Lake Forest, California, United States Recruiting

Study contacts

• Study coordinator: Study Project Manager
• Email: axr@pavmed.com
• Phone: 917-813-1828

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using a swallowable sponge to collect esophageal samples for Barrett's esophagus detection

  This study is testing a swallowable sponge to see if it can safely collect samples from the esophagus to help detect Barrett's esophagus and esophageal cancer in patients who may have these conditions.

  Recruiting at 3 sites Mayo Clinic · Scottsdale, Arizona and 4 other locations · NCT06071845

• Comparing surveillance and therapy for Barrett's esophagus with low-grade dysplasia

  This study is testing whether regular check-ups or a treatment to remove precancerous cells is better for people with Barrett's esophagus and low-grade dysplasia.

  Recruiting at 28 sites University of Colorado, Denver · Birmingham, Alabama and 29 other locations · NCT05753748

• Comparing two methods for sampling Barrett's esophagus

  This study is testing which method, the standard biopsy or a new sampling technique, is better at finding early signs of cancer in people with Barrett's esophagus.

  Recruiting at 14 sites University of Colorado, Denver · Gilbert, Arizona and 13 other locations · NCT05530343

• Itraconazole with endoscopic ablation to prevent esophageal cancer in high‑risk Barrett's esophagus

  This study tests if adding itraconazole to the standard endoscopic ablation can better prevent esophageal cancer in people with high-risk Barrett's esophagus.

  Recruiting at 4 sites Phase 2 National Cancer Institute (NCI) · Kansas City, Kansas and 5 other locations · NCT06732388

• Detecting Barrett's Esophagus in Patients Without GERD Symptoms

  This study is testing a new way to find Barrett's esophagus in people who don’t have GERD symptoms by using a simple capsule test instead of the usual endoscopy.

  Recruiting at 5 sites Case Comprehensive Cancer Center · Aurora, Colorado and 4 other locations · NCT06687603

• Assessing Barrett's Esophagus in Patients with Anorexia Nervosa and Purging Behaviors

  This study is trying to see if people with anorexia nervosa who purge have Barrett's esophagus, using non-invasive tests to check for this condition in patients aged 18-65.

  Recruiting at 3 sites Denver Health and Hospital Authority · Denver, Colorado and 2 other locations · NCT06532734

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.