Registry for patients receiving proton radiation therapy

Proton Radiation Therapy Registry

Observational Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · NCT04376229

This study is collecting information from patients who receive proton radiation therapy to see how well it works and who benefits the most from it.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorSidney Kimmel Comprehensive Cancer Center at Johns Hopkins Academic / other
Drugs / interventionsradiation
Locations4 sites (Washington D.C., District of Columbia and 3 other locations)
Trial IDNCT04376229 on ClinicalTrials.gov

What this trial studies

The Johns Hopkins Proton Therapy center is creating a registry to collect detailed information on patients treated with proton radiation therapy, including 3D radiation dosimetry, baseline clinical data, and outcomes related to disease, toxicity, and quality of life. This observational approach aims to include all patients treated at the center to facilitate future comparisons of treatment outcomes. By capturing comprehensive data, the registry seeks to enhance understanding of which patient populations benefit most from proton therapy, despite its higher costs compared to traditional photon therapy.

Who should consider this trial

Good fit: Ideal candidates for this registry are all patients receiving treatment at the Johns Hopkins Proton Therapy center.

Not a fit: Patients who are not receiving proton therapy or those treated at facilities other than the designated proton center will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could help identify which patients are most likely to benefit from proton therapy, leading to improved treatment decisions and outcomes.

How similar studies have performed: Other studies utilizing registries for treatment outcomes have shown success in improving patient care and understanding treatment efficacy, making this approach promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients treated at the proton center.

Exclusion Criteria:

* Any other than what is supplied in the inclusion criteria

Where this trial is running

Washington D.C., District of Columbia and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cancer, Therapy-Relatedproton therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.