Registry for patients receiving proton radiation therapy
Official title: Proton Radiation Therapy Registry
Run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · NCT04376229 · Data updated 2026-11-12
This study is collecting information from patients who receive proton radiation therapy to see how well it works and who benefits the most from it.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Academic / other |
| Drugs / interventions | radiation |
| Locations | 4 sites (Washington D.C., District of Columbia and 3 other locations) |
| Status | Recruiting |
| Started | April 7, 2020 |
| Main results expected | December 2030 |
| Study ends | December 2040 |
| Registry record updated | June 30, 2026 |
| Trial ID | NCT04376229 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are all patients receiving treatment at the Johns Hopkins Proton Therapy center.
✕Probably not a fit
Patients who are not receiving proton therapy or those treated at facilities other than the designated proton center will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Johns Hopkins Proton Therapy center is creating a registry to collect detailed information on patients treated with proton radiation therapy, including 3D radiation dosimetry, baseline clinical data, and outcomes related to disease, toxicity, and quality of life. This observational approach aims to include all patients treated at the center to facilitate future comparisons of treatment outcomes. By capturing comprehensive data, the registry seeks to enhance understanding of which patient populations benefit most from proton therapy, despite its higher costs compared to traditional photon therapy.
Why it matters
Potential benefit: If successful, this registry could help identify which patients are most likely to benefit from proton therapy, leading to improved treatment decisions and outcomes.
How similar studies have gone: Other studies utilizing registries for treatment outcomes have shown success in improving patient care and understanding treatment efficacy, making this approach promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients treated at the proton center. Exclusion Criteria: * Any other than what is supplied in the inclusion criteria
Where it's running
-
Sibley Memorial Hospital
Washington D.C., District of Columbia, United States Recruiting -
Suburban Hospital
Washington D.C., District of Columbia, United States Recruiting -
Bayview Hospital
Baltimore, Maryland, United States Recruiting -
Johns Hopkins Hospital
Baltimore, Maryland, United States Recruiting
Study contacts
- Principal investigator: Curtiland Deville, MD — Johns Hopkins University
- Study coordinator: Akila Viswanathan, MD
- Email: anv@jhmi.edu
- Phone: 410-502-1421
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.