Clinical trial Recruiting at 4 sites Observational Ages 18 to 100

Registry for patients receiving proton radiation therapy

Official title: Proton Radiation Therapy Registry

Run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · NCT04376229 · Data updated 2026-11-12

This study is collecting information from patients who receive proton radiation therapy to see how well it works and who benefits the most from it.

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment5000 (estimated)
SponsorSidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Academic / other
Drugs / interventionsradiation
Locations4 sites (Washington D.C., District of Columbia and 3 other locations)
StatusRecruiting
StartedApril 7, 2020
Main results expectedDecember 2030
Study endsDecember 2040
Registry record updatedJune 30, 2026
Trial IDNCT04376229 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this registry are all patients receiving treatment at the Johns Hopkins Proton Therapy center.

Probably not a fit

Patients who are not receiving proton therapy or those treated at facilities other than the designated proton center will not benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Johns Hopkins Proton Therapy center is creating a registry to collect detailed information on patients treated with proton radiation therapy, including 3D radiation dosimetry, baseline clinical data, and outcomes related to disease, toxicity, and quality of life. This observational approach aims to include all patients treated at the center to facilitate future comparisons of treatment outcomes. By capturing comprehensive data, the registry seeks to enhance understanding of which patient populations benefit most from proton therapy, despite its higher costs compared to traditional photon therapy.

Why it matters

Potential benefit: If successful, this registry could help identify which patients are most likely to benefit from proton therapy, leading to improved treatment decisions and outcomes.

How similar studies have gone: Other studies utilizing registries for treatment outcomes have shown success in improving patient care and understanding treatment efficacy, making this approach promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients treated at the proton center.

Exclusion Criteria:

* Any other than what is supplied in the inclusion criteria

Where it's running

  • Sibley Memorial Hospital
    Washington D.C., District of Columbia, United States
    Recruiting
  • Suburban Hospital
    Washington D.C., District of Columbia, United States
    Recruiting
  • Bayview Hospital
    Baltimore, Maryland, United States
    Recruiting
  • Johns Hopkins Hospital
    Baltimore, Maryland, United States
    Recruiting

Study contacts

  • Principal investigator: Curtiland Deville, MD — Johns Hopkins University
  • Study coordinator: Akila Viswanathan, MD
  • Email: anv@jhmi.edu
  • Phone: 410-502-1421

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.