Registry for patients receiving ECMO or Impella devices

Clinical Outcomes in Patients in Need of a Non-permanent Extracorporeal Cardiocirculatory Support System (Peripheral Extracorporeal Membrane Oxygenation (ECMO) or Axial Flow Pump IMPELLA)

Observational Insel Gruppe AG, University Hospital Bern · NCT04117230

This study is gathering information from patients who are receiving ECMO or Impella devices to see how well these treatments work for heart problems.

Quick facts

Study typeObservational
Enrollment1500 (estimated)
Ages18 Years and up
SexAll
SponsorInsel Gruppe AG, University Hospital Bern Academic / other
Locations5 sites (Basel and 4 other locations)
Trial IDNCT04117230 on ClinicalTrials.gov

What this trial studies

This observational registry aims to collect baseline clinical and procedural data from patients undergoing ECMO or Impella implantation across multiple sites. It includes all eligible patients who consent to participate, allowing for a comprehensive assessment of clinical outcomes. The data collected will help evaluate the effectiveness and safety of these circulatory support devices in treating cardiogenic shock. The registry operates independently of the treating physician's decisions regarding device use.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who require implantation of a peripheral cannulated VA-ECMO or Impella device.

Not a fit: Patients who do not meet the medical criteria for ECMO or Impella implantation will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could enhance understanding of treatment outcomes and improve care for patients with cardiogenic shock.

How similar studies have performed: Other studies have shown success with similar observational registries, indicating the potential for valuable insights into patient outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 18 years
* Medical indication for implantation of a peripheral cannulated VA-ECMO or microaxial flow pump (IMPELLA) or newer LV / LA-Ascending Aorta devices.
* Signed informed consent by patient or relative or waived consent by EC

Exclusion Criteria:

* None

Where this trial is running

Basel and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiogenic Shock
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.