Clinical trial Recruiting at 1 site Observational Ages 18 and up

Registry for patients needing massive blood transfusions in Australia and New Zealand

Official title: Improving Outcomes for Patients With Critical Bleeding Requiring Massive Transfusion

Run by Monash University · NCT02863250 · Data updated 2026-11-12

This study is collecting information from patients in Australia and New Zealand who need large blood transfusions to help improve treatment and outcomes for future patients.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50000 (estimated)
SponsorMonash University
Academic / other
Locations1 site (Melbourne, Victoria)
StatusRecruiting
StartedMarch 2011
Main results expectedDecember 31, 2028
Study endsDecember 31, 2028
Registry record updatedSeptember 2, 2020
Trial IDNCT02863250 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this registry are individuals aged 18 years or older who have received five or more units of red blood cells within a four-hour period.

Probably not a fit

Patients who do not experience massive transfusions or are under 18 years of age may not benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Australian and New Zealand Massive Transfusion Registry (ANZ-MTR) collects and analyzes data from patients who have experienced significant blood loss requiring massive transfusions across various clinical settings, including trauma and surgery. By utilizing electronic data extraction and linkage methodologies, the registry compiles information from multiple hospital sources to improve understanding of transfusion practices and patient outcomes. With over 6,000 patients already included, the ANZ-MTR aims to transition into a sustainable operational model that aligns with national safety and quality frameworks while facilitating ongoing research opportunities.

Why it matters

Potential benefit: If successful, this registry could lead to improved transfusion practices and better patient outcomes for those experiencing severe bleeding.

How similar studies have gone: Other similar registries have shown success in improving clinical practices and patient outcomes, indicating that this approach is promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged 18 years or over
* 5 or more units of red blood cells in any 4 hour period

Exclusion Criteria:

* nil

Where it's running

  • Monash University
    Melbourne, Victoria, Australia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.