Registry for patients needing massive blood transfusions in Australia and New Zealand

Improving Outcomes for Patients With Critical Bleeding Requiring Massive Transfusion

Monash University · NCT02863250

This study is collecting information from patients in Australia and New Zealand who need large blood transfusions to help improve treatment and outcomes for future patients.

Quick facts

Study typeObservational
Enrollment50000 (estimated)
Ages18 Years and up
SexAll
SponsorMonash University (other)
Locations1 site (Melbourne, Victoria)
Trial IDNCT02863250 on ClinicalTrials.gov

What this trial studies

The Australian and New Zealand Massive Transfusion Registry (ANZ-MTR) collects and analyzes data from patients who have experienced significant blood loss requiring massive transfusions across various clinical settings, including trauma and surgery. By utilizing electronic data extraction and linkage methodologies, the registry compiles information from multiple hospital sources to improve understanding of transfusion practices and patient outcomes. With over 6,000 patients already included, the ANZ-MTR aims to transition into a sustainable operational model that aligns with national safety and quality frameworks while facilitating ongoing research opportunities.

Who should consider this trial

Good fit: Ideal candidates for this registry are individuals aged 18 years or older who have received five or more units of red blood cells within a four-hour period.

Not a fit: Patients who do not experience massive transfusions or are under 18 years of age may not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could lead to improved transfusion practices and better patient outcomes for those experiencing severe bleeding.

How similar studies have performed: Other similar registries have shown success in improving clinical practices and patient outcomes, indicating that this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged 18 years or over
* 5 or more units of red blood cells in any 4 hour period

Exclusion Criteria:

* nil

Where this trial is running

Melbourne, Victoria

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Massive Transfusion, Trauma, Cardiothoracic Surgery, Gastrointestinal Bleeding, Vascular Surgery, Obstetric Bleeding, Liver Transplant

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.