Registry for outcomes of percutaneous tricuspid valve repair

Pforzheim Tricuspid Valve Registry: A Real-world Observational Trial Evaluating Outcomes in Patients Treated With the Abbott TriClip™ Device in Helios Klinikum Pforzheim

Helios Klinikum Pforzheim · NCT05179616

This study is testing how well the TriClip™ device works for treating severe tricuspid regurgitation in critically ill patients who still have symptoms despite taking medication.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorHelios Klinikum Pforzheim (other)
Locations1 site (Pforzheim)
Trial IDNCT05179616 on ClinicalTrials.gov

What this trial studies

The Pforzheim Tricuspid Valve Registry aims to evaluate the safety and effectiveness of the TriClip™ device in treating severe tricuspid regurgitation in critically ill patients. This observational study is conducted in a single-center, open-label format, focusing on patients who are symptomatic despite medical therapy. The registry will collect data on patient outcomes following the transcatheter edge-to-edge tricuspid valve repair procedure, providing insights into its real-world application and performance.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with severe tricuspid regurgitation who remain symptomatic despite medical therapy.

Not a fit: Patients who are participating in another clinical study that may affect the outcomes of this registry will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could offer a less invasive treatment option for patients suffering from severe tricuspid regurgitation and improve their quality of life.

How similar studies have performed: Other studies have shown promising results with similar percutaneous approaches for treating tricuspid regurgitation, but this specific registry focuses on the newly approved TriClip™ device.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects (\>=18 years age) have severe tricuspid regurgitation and are symptomatic despite medical therapy.
* Subjects eligible to receive the TriClip™
* Subjects must provide written informed consent prior to study procedure.

Exclusion Criteria:

* Subjects participating in another clinical study that may impact the follow-up or results of this study.

Where this trial is running

Pforzheim

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Tricuspid Regurgitation, Right Heart Failure, Cardiac Remodeling, Ventricular, Cardiac Remodeling, Atrial

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.