Registry for Myasthenia Gravis patients at Yale University
Official title: Exploring Outcomes and Characteristics of Myasthenia Gravis: The EXPLORE MG Registry
Run by Yale University · NCT03792659 · Data updated 2026-11-12
This study is collecting information from people with Myasthenia Gravis at Yale University to help understand the disease better and improve care for patients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | Yale University Academic / other |
| Locations | 1 site (New Haven, Connecticut) |
| Status | Recruiting |
| Started | March 30, 2016 |
| Main results expected | September 30, 2026 |
| Study ends | October 30, 2026 |
| Registry record updated | November 28, 2025 |
| Trial ID | NCT03792659 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are adult patients diagnosed with Myasthenia Gravis who are receiving care at the Yale Department of Neurology.
✕Probably not a fit
Patients who do not have a diagnosis of Myasthenia Gravis will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This registry aims to collect and analyze data from patients diagnosed with Myasthenia Gravis (MG) at Yale University. It will gather biological specimens, clinical data, and information on disease management, healthcare utilization, and treatment outcomes. By studying these various aspects, the registry will enhance understanding of MG and support future research initiatives. The data collected will be instrumental in answering critical questions about the disease and improving patient care.
Why it matters
Potential benefit: If successful, this registry could lead to improved understanding and management of Myasthenia Gravis, ultimately enhancing patient outcomes.
How similar studies have gone: Other registries focusing on chronic conditions have shown success in advancing research and improving patient care, indicating a positive outlook for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients diagnosed with Myasthenia Gravis presenting to the Yale Department of Neurology for clinical care or research interventions will be invited to donate their biological specimens/clinical data. Exclusion Criteria: * Failure to meet the Inclusion Criteria.
Where it's running
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Yale-New Haven Hospital
New Haven, Connecticut, United States Recruiting
Study contacts
- Principal investigator: Richard Nowak, MD, MS — Assistant Professor, Yale University
- Study coordinator: Bailey Sheldon, PhD
- Email: bailey.munrosheldon@yale.edu
- Phone: 203-737-7095
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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MG patient registry to track long-term experiences and treatment patterns
This registry collects information from adults with myasthenia gravis to see how symptoms and quality of life change over time and how treatments relate to those changes.
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Ublituximab maintenance after efgartigimod response in myasthenia gravis
This study tests whether giving ublituximab as maintenance after a positive response to efgartigimod helps adults with myasthenia gravis.
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Pregnant Women with Neuroimmune Diseases: A long-term follow-up study
This study follows women with neuroimmune diseases and healthy controls through pregnancy and up to ten years to see how pregnancy affects disease activity and outcomes for both mother and baby.
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Early ravulizumab for adults with myasthenic crisis in the ICU
This project will test whether giving ravulizumab early to adults with AChR-positive generalized myasthenia gravis who are in the ICU for a myasthenic crisis helps speed recovery.
-
KITE-363 treatment for relapsed or refractory autoimmune neurologic diseases
This study will test whether KITE-363 is safe and can help people with relapsed or treatment-resistant autoimmune neurologic diseases such as MS, CIDP, and myasthenia gravis.
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ADAPT Forward master protocol testing multiple regimens for generalized myasthenia gravis
This platform tests several drug regimens, including efgartigimod IV and empasiprubart IV, in adults with generalized myasthenia gravis to find safer and more effective treatment combinations.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.