Registry for managing outcomes in patients with atrial fibrillation
Official title: MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)
Run by CorVita Science Foundation · NCT05978466 · Data updated 2026-11-12
This study is creating a registry to track how patients with atrial fibrillation are treated and their outcomes, aiming to improve care and reduce the risk of complications like strokes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | CorVita Science Foundation Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | December 22, 2017 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | January 18, 2024 |
| Trial ID | NCT05978466 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults diagnosed with either valvular or non-valvular atrial fibrillation.
✕Probably not a fit
Patients under 18 years old or those with a clinical prognosis of death within six months may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research aims to gather data on the management of patients diagnosed with atrial fibrillation (AF), a condition characterized by irregular heartbeats that increase the risk of stroke. The study will create a registry to track treatment patterns and outcomes, including the prevention of thrombo-embolic events and the effectiveness of various interventions. By documenting the natural history of AF and associated complications, the registry will help identify trends in patient care across different demographics and treatment approaches. The goal is to improve understanding and management of AF to enhance patient outcomes.
Why it matters
Potential benefit: If successful, this registry could lead to improved management strategies for patients with atrial fibrillation, potentially reducing the risk of stroke and other complications.
How similar studies have gone: Other studies have successfully utilized registries to improve understanding and management of atrial fibrillation, indicating that this approach has potential for meaningful insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Diagnosis of valvular or non valvular atrial fibrillation 2. ECG documented atrial fibrillation A. 12 lead B. Rhythm strip C. Event monitor D. Holter Monitor E. Implantable loop recorder Exclusion Criteria: 1. Age below 18 years. 2. Clinical evidence that death within 6 months is possible 3. Inability to consent to the research or sign a consent form 4. Inability to follow up at the research clinic at least annually for continuity of AF care and management
Where it's running
-
CorVita Science Foundation (NFP)
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Martin C Burke, DO — Chief Scientific Officer
- Study coordinator: Edward M Burke
- Email: eddie@corvitahealth.org
- Phone: 773-432-4888
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
-
Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities
This study tests how comorbid conditions like sleep apnea and primary aldosteronism relate to left-atrial fibrosis and AF recurrence in patients undergoing ablation.
-
Dual Energy ablation with SmartTouch SF catheter in persistent atrial fibrillation
This study tests a pulsed field and radiofrequency ablation system to treat persistent atrial fibrillation in adults who have not responded well to prior medications.
-
Identifying AF patients who may need more than standard ablation using Volta AF-Xplorer II
This trial tests whether AI-identified dispersion areas during AF ablation can predict recurrence after a standard pulmonary vein isolation in patients with persistent AF.
-
4D intracardiac echocardiography to guide left atrial appendage occlusion procedures
A new 4D ICE catheter is being tested alongside standard imaging to see if it can safely guide left atrial appendage occlusion procedures for adults with atrial fibrillation.
-
Thoracoscopic vs Catheter Ablation as the First Rhythm Control in Atrial Fibrillation with a Large Left Atrium
This trial tests whether thoracoscopic surgical ablation is better at keeping atrial fibrillation under control than catheter ablation in people with persistent AF and a large left atrium who have not had an ablation before.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.