Registry for managing liver failure in Chinese patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a real-world case registry database for inpatients suffering from liver failure in China. It will utilize an electronic clinical data collection system across multiple centers to analyze clinical characteristics, the epidemiology of infections, and the effects of sarcopenia on patient outcomes. The findings will help optimize treatment strategies, including antiviral therapies and artificial liver support, and will inform future studies on related clinical issues. The study focuses on understanding the complexities of liver failure and its management in the Chinese population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients with a diagnosis consistent with liver failure and pre-liver failure:

* Extreme weakness with significant gastrointestinal symptoms such as anorexia, vomiting and abdominal distention;
* Elevated alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) with progressive jaundice (TBil≥85.5 μmol/L);
* Bleeding tendency with PTA ≤ 60% or INR ≥ 1.5.

Exclusion Criteria:

* An event or complication that, in the judgment of the investigator, significantly affects the assessment of clinical status.

Where it's running

• First Affiliated Hospital of Xi'an Jiaotong University
  Xi'an, Shaanxi, China Recruiting
• Ankang Central Hospital
  Ankang, China Recruiting
• The Second Affiliated Hospital of Xi'an Jiaotong University
  Xi'an, China Recruiting
• Xianyang Central Hospital
  Xianyang, China Recruiting
• Xiangya Hospital of Central South University
  Changsha, China Not yet recruiting
• Hanzhong 3201 Hospital
  Hanzhong, China Not yet recruiting

Study contacts

• Study coordinator: Yingli He, Pro.
• Email: heyingli2000@xjtu.edu.cn
• Phone: 0086-18991232863

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.