Clinical trial Recruiting at 22 sites Observational

Registry for liver transplant outcomes using OCS liver perfusion

Official title: US National OCS Liver Perfusion (OLP) Registry

Run by TransMedics · NCT05940857 · Data updated 2026-11-12

This study is collecting information on liver transplant patients who received their organs using a special machine to see how well it works compared to other methods.

Quick facts

Study typeObservational
SexAll
Enrollment100000 (estimated)
SponsorTransMedics
Industry-sponsored
Locations22 sites (Birmingham, Alabama and 21 other locations)
StatusRecruiting
StartedOctober 14, 2021
Main results expectedOctober 2031
Study endsOctober 2031
Registry record updatedAugust 16, 2024
Trial IDNCT05940857 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this registry are all individuals who have received a liver transplant.

Probably not a fit

Patients who have not undergone liver transplantation will not benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry collects data on liver transplant recipients who have undergone transplantation using Organ Care System (OCS) liver perfusion, as well as those who have received transplants using other preservation methods. The registry is sponsored by TransMedics and involves multiple centers across the U.S., with oversight from the United Network for Organ Sharing (UNOS). Data will be gathered from the national transplant outcomes registry and supplemented by additional information from participating centers. The goal is to analyze and compare outcomes to improve liver transplant practices.

Why it matters

Potential benefit: If successful, this registry could enhance understanding of liver transplant outcomes and improve patient care strategies.

How similar studies have gone: Other observational studies have shown success in improving transplant outcomes through data collection and analysis, making this approach promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
All liver transplant recipients.

Where it's running

  • University of Alabama
    Birmingham, Alabama, United States
    Recruiting
  • Mayo Clinic Hospital Arizona
    Phoenix, Arizona, United States
    Recruiting
  • University of California San Diego
    La Jolla, California, United States
    Recruiting
  • University of California San Francisco
    San Francisco, California, United States
    Recruiting
  • Mayo Clinic Hospital Florida
    Jacksonville, Florida, United States
    Recruiting
  • Emory University Hospital
    Atlanta, Georgia, United States
    Recruiting
Show 16 more locations
  • University of Kentucky Medical Center
    Lexington, Kentucky, United States
    Recruiting
  • Beth Israel Deaconess Medical Center
    Boston, Massachusetts, United States
    Recruiting
  • Lahey Clinic Medical Center
    Burlington, Massachusetts, United States
    Recruiting
  • University of Michigan Medical Center
    Ann Arbor, Michigan, United States
    Recruiting
  • Henry Ford Hospital
    Detroit, Michigan, United States
    Recruiting
  • Mayo Clinic Hospital Minnesota
    Rochester, Minnesota, United States
    Recruiting
  • SSM Health Saint Louis University Hospital
    St Louis, Missouri, United States
    Recruiting
  • University of Nebraska Medical Center
    Omaha, Nebraska, United States
    Recruiting
  • NY Presbyterian Hospital/Columbia Univ. Medical Center
    New York, New York, United States
    Recruiting
  • Carolinas Medical Center/Atrium Health
    Charlotte, North Carolina, United States
    Recruiting
  • Duke Medical Center
    Durham, North Carolina, United States
    Recruiting
  • Thomas Jefferson University Hospital
    Philadelphia, Pennsylvania, United States
    Recruiting
  • UT Southwestern Medical Center
    Dallas, Texas, United States
    Recruiting
  • Houston Methodist
    Houston, Texas, United States
    Recruiting
  • University Hospital, University of Texas Health Science Center
    San Antonio, Texas, United States
    Recruiting
  • University of Utah Medical Center
    Salt Lake City, Utah, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.