Registry for liver transplant outcomes using OCS liver perfusion
US National OCS Liver Perfusion (OLP) Registry
This study is collecting information on liver transplant patients who received their organs using a special machine to see how well it works compared to other methods.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100000 (estimated) |
| Sex | All |
| Sponsor | TransMedics Industry-sponsored |
| Locations | 22 sites (Birmingham, Alabama and 21 other locations) |
| Trial ID | NCT05940857 on ClinicalTrials.gov |
What this trial studies
This observational registry collects data on liver transplant recipients who have undergone transplantation using Organ Care System (OCS) liver perfusion, as well as those who have received transplants using other preservation methods. The registry is sponsored by TransMedics and involves multiple centers across the U.S., with oversight from the United Network for Organ Sharing (UNOS). Data will be gathered from the national transplant outcomes registry and supplemented by additional information from participating centers. The goal is to analyze and compare outcomes to improve liver transplant practices.
Who should consider this trial
Good fit: Ideal candidates for this registry are all individuals who have received a liver transplant.
Not a fit: Patients who have not undergone liver transplantation will not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of liver transplant outcomes and improve patient care strategies.
How similar studies have performed: Other observational studies have shown success in improving transplant outcomes through data collection and analysis, making this approach promising.
Eligibility criteria
Show full inclusion / exclusion criteria
All liver transplant recipients.
Where this trial is running
Birmingham, Alabama and 21 other locations
- University of Alabama — Birmingham, Alabama, United States (Recruiting)
- Mayo Clinic Hospital Arizona — Phoenix, Arizona, United States (Recruiting)
- University of California San Diego — La Jolla, California, United States (Recruiting)
- University of California San Francisco — San Francisco, California, United States (Recruiting)
- Mayo Clinic Hospital Florida — Jacksonville, Florida, United States (Recruiting)
- Emory University Hospital — Atlanta, Georgia, United States (Recruiting)
- University of Kentucky Medical Center — Lexington, Kentucky, United States (Recruiting)
- Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States (Recruiting)
- Lahey Clinic Medical Center — Burlington, Massachusetts, United States (Recruiting)
- University of Michigan Medical Center — Ann Arbor, Michigan, United States (Recruiting)
- Henry Ford Hospital — Detroit, Michigan, United States (Recruiting)
- Mayo Clinic Hospital Minnesota — Rochester, Minnesota, United States (Recruiting)
- SSM Health Saint Louis University Hospital — St Louis, Missouri, United States (Recruiting)
- University of Nebraska Medical Center — Omaha, Nebraska, United States (Recruiting)
- NY Presbyterian Hospital/Columbia Univ. Medical Center — New York, New York, United States (Recruiting)
- Carolinas Medical Center/Atrium Health — Charlotte, North Carolina, United States (Recruiting)
- Duke Medical Center — Durham, North Carolina, United States (Recruiting)
- Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States (Recruiting)
- UT Southwestern Medical Center — Dallas, Texas, United States (Recruiting)
- Houston Methodist — Houston, Texas, United States (Recruiting)
- University Hospital, University of Texas Health Science Center — San Antonio, Texas, United States (Recruiting)
- University of Utah Medical Center — Salt Lake City, Utah, United States (Recruiting)
Study contacts
- Study coordinator: Kelly Jork
- Email: kjork@transmedics.com
- Phone: 978-494-3918
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.