Registry for liver transplant outcomes using OCS liver perfusion
Official title: US National OCS Liver Perfusion (OLP) Registry
Run by TransMedics · NCT05940857 · Data updated 2026-11-12
This study is collecting information on liver transplant patients who received their organs using a special machine to see how well it works compared to other methods.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 100000 (estimated) |
| Sponsor | TransMedics Industry-sponsored |
| Locations | 22 sites (Birmingham, Alabama and 21 other locations) |
| Status | Recruiting |
| Started | October 14, 2021 |
| Main results expected | October 2031 |
| Study ends | October 2031 |
| Registry record updated | August 16, 2024 |
| Trial ID | NCT05940857 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this registry are all individuals who have received a liver transplant.
✕Probably not a fit
Patients who have not undergone liver transplantation will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational registry collects data on liver transplant recipients who have undergone transplantation using Organ Care System (OCS) liver perfusion, as well as those who have received transplants using other preservation methods. The registry is sponsored by TransMedics and involves multiple centers across the U.S., with oversight from the United Network for Organ Sharing (UNOS). Data will be gathered from the national transplant outcomes registry and supplemented by additional information from participating centers. The goal is to analyze and compare outcomes to improve liver transplant practices.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of liver transplant outcomes and improve patient care strategies.
How similar studies have gone: Other observational studies have shown success in improving transplant outcomes through data collection and analysis, making this approach promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
All liver transplant recipients.
Where it's running
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University of Alabama
Birmingham, Alabama, United States Recruiting -
Mayo Clinic Hospital Arizona
Phoenix, Arizona, United States Recruiting -
University of California San Diego
La Jolla, California, United States Recruiting -
University of California San Francisco
San Francisco, California, United States Recruiting -
Mayo Clinic Hospital Florida
Jacksonville, Florida, United States Recruiting -
Emory University Hospital
Atlanta, Georgia, United States Recruiting
Show 16 more locations
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University of Kentucky Medical Center
Lexington, Kentucky, United States Recruiting -
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States Recruiting -
Lahey Clinic Medical Center
Burlington, Massachusetts, United States Recruiting -
University of Michigan Medical Center
Ann Arbor, Michigan, United States Recruiting -
Henry Ford Hospital
Detroit, Michigan, United States Recruiting -
Mayo Clinic Hospital Minnesota
Rochester, Minnesota, United States Recruiting -
SSM Health Saint Louis University Hospital
St Louis, Missouri, United States Recruiting -
University of Nebraska Medical Center
Omaha, Nebraska, United States Recruiting -
NY Presbyterian Hospital/Columbia Univ. Medical Center
New York, New York, United States Recruiting -
Carolinas Medical Center/Atrium Health
Charlotte, North Carolina, United States Recruiting -
Duke Medical Center
Durham, North Carolina, United States Recruiting -
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States Recruiting -
UT Southwestern Medical Center
Dallas, Texas, United States Recruiting -
Houston Methodist
Houston, Texas, United States Recruiting -
University Hospital, University of Texas Health Science Center
San Antonio, Texas, United States Recruiting -
University of Utah Medical Center
Salt Lake City, Utah, United States Recruiting
Study contacts
- Study coordinator: Kelly Jork
- Email: kjork@transmedics.com
- Phone: 978-494-3918
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Expanding HIV-positive donor livers for HIV-positive recipients
This study tests whether liver transplants from HIV-positive donors to HIV-positive recipients are safe regarding opportunistic infections and cancer.
-
Magnetic Resonance Cholangiopancreatography to help living liver donors and their recipients
This study tests whether preoperative MRCP imaging can help select living liver donors and reduce biliary complications in recipients.
-
Reducing Immunosuppression by 50% in Young Liver Transplant Recipients
This study tests whether cutting the immunosuppressive medicine by half in children with liver transplants is safe and effective.
-
Preoperative Carbohydrate Loading Before Liver Transplant
This study tests whether drinking a carbohydrate beverage before anesthesia helps liver transplant patients recover faster.
-
Doctor counseling plus smartphone apps to support healthy eating and activity after liver or kidney transplant
This program tries whether doctor-delivered lifestyle counseling combined with two smartphone apps can help people aged 60 and older who had a liver or kidney transplant eat healthier and be more active.
-
Long-term health of children born to mothers who had a solid organ transplant
This project will look for long-term heart, kidney, and immune system problems in people aged 16 and older who were born to mothers who had a kidney, liver, pancreas, heart, or lung transplant.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.