Registry for invasive Candida infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The ECMM Candida Registry (CandiReg) aims to enhance understanding of invasive Candida infections by documenting their global incidence, clinical patterns, and antifungal resistance. This observational study will collect data on patient demographics, risk factors, and treatment regimens to inform future guidelines and improve patient outcomes. It will also establish a collection of isolates for molecular characterization and resistance gene evaluation. The registry will serve as a platform for future studies and outbreak responses.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Cultural, histopathological, antigen or DNA evidence of invasive fungal infection with Candida species.
* Hepatosplenic candidiasis with signs of disseminated Candida infection without culture, histological or microscopic evidence
* Case control

Matching procedure for controls:

In part, controls will be included at the same hospitals that include cases (i.e. each one control per case, both in the same hospital).

Controls will be matched by demographics, underlying diseases and risk factors as well as duration of hospitalization

Exclusion Criteria:

\- Colonization or other non-invasive infection, including superficial skin infections, candiduria without dissemination or Candida spp. in stool.

Where it's running

• University Hospital Cologne
  Cologne, North Rhine-Westphalia, Germany Recruiting

Study contacts

• Study coordinator: Oliver Cornely, MD
• Email: oliver.cornely@uk-koeln.de
• Phone: +49 221 478

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.