Registry for HER2-positive breast cancer patients
Official title: Prospective Evaluation of Outcomes for HER2-positive Breast Cancer (PRO-HER2)
Run by University of Kansas Medical Center · NCT06603597 · Data updated 2026-11-12
This study is collecting information from people with HER2-positive breast cancer to see how different factors affect their treatment outcomes and overall care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University of Kansas Medical Center Academic / other |
| Locations | 6 sites (Overland Park, Kansas and 5 other locations) |
| Status | Recruiting |
| Started | September 27, 2024 |
| Main results expected | October 2044 |
| Study ends | October 2044 |
| Registry record updated | July 17, 2026 |
| Trial ID | NCT06603597 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with stage I-IV HER2-positive breast cancer.
✕Probably not a fit
Patients with other types of breast cancer or those who do not meet the HER2-positive criteria may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to gather data on patients with HER2-positive breast cancer to explore the relationships between various patient and tumor characteristics and their outcomes. By collecting and analyzing this information, researchers hope to identify patterns that could inform treatment decisions and improve patient care. The study will include patients at different stages of HER2-positive breast cancer, allowing for a comprehensive understanding of the disease.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and outcomes for patients with HER2-positive breast cancer.
How similar studies have gone: Other observational studies focusing on breast cancer characteristics have shown success in identifying important links that can enhance patient management.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Stage I-IV HER2-positive breast cancer Exclusion Criteria: * None
Where it's running
-
The University of Kansas Cancer Center
Westwood, Kansas, United States Recruiting -
KUCC - Indian Creek
Overland Park, Kansas, United States Active not recruiting -
KUCC - Overland Park
Overland Park, Kansas, United States Active not recruiting -
KUCC - Briarcliff
Westwood, Kansas, United States Active not recruiting -
KUCC - Olathe
Westwood, Kansas, United States Active not recruiting -
KUCC - Lee's Summit
Lee's Summit, Missouri, United States Active not recruiting
Study contacts
- Study coordinator: Study Coordinator
- Email: PRO-HER2@kumc.edu
- Phone: 913-588-6079
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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This trial tests a paclitaxel oral solution given with trastuzumab and pertuzumab to see if a safe dose can be found for women with HER2-positive breast cancer before they have surgery.
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Olaparib with Trastuzumab and Pertuzumab before surgery for older women with HER2-positive breast cancer
This trial tests whether adding olaparib to standard HER2-targeted therapy can help older women with newly diagnosed, operable HER2-positive breast cancer before surgery.
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Pyrotinib-based regimens for advanced HER2-positive breast cancer: real-world sequential therapy after progression
This real-world study tests whether giving disitamab vedotin after pyrotinib-based treatment helps people with advanced HER2-positive breast cancer.
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Pre-surgery trastuzumab deruxtecan (SHR-A1811) plus pertuzumab for HER2-positive breast cancer
This trial tests giving trastuzumab deruxtecan (SHR-A1811) with pertuzumab before surgery to see if it helps women with stage II–III HER2-positive breast cancer achieve a complete response.
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This will test whether combining HLX22 with HLX87 helps adults with HER2-positive recurrent or metastatic breast cancer when given as a first-line treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.