Registry for endovascular treatment of acute ischemic stroke in Germany
Official title: German Stroke Registry - Endovascular Treatment
Run by Universitätsklinikum Hamburg-Eppendorf · NCT03356392 · Data updated 2026-11-12
This study is collecting information from patients in Germany who are receiving special procedures for acute ischemic stroke to see how well these treatments work and how safe they are.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg, Free and Hanseatic City of Hamburg) |
| Status | Recruiting |
| Started | June 2015 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | December 11, 2024 |
| Trial ID | NCT03356392 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years with a clinical diagnosis of acute ischemic stroke who are eligible for intravenous thrombolysis.
✕Probably not a fit
Patients who do not have a confirmed diagnosis of persistent occlusion of relevant arteries or those who are not eligible for intravenous thrombolysis may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The German Stroke Registry - Endovascular Treatment is an observational study that enrolls patients treated with endovascular stroke interventions across multiple stroke centers in Germany. It collects comprehensive data on patient demographics, clinical assessments, procedural details, and follow-up outcomes for up to 90 days post-stroke. The study aims to gather real-world evidence on the effectiveness and safety of endovascular treatments for acute ischemic stroke. Data is collected as part of routine clinical care, ensuring a robust dataset for analysis.
Why it matters
Potential benefit: If successful, this registry could improve understanding of endovascular treatment outcomes, leading to enhanced patient care and treatment protocols for acute ischemic stroke.
How similar studies have gone: Other observational studies on endovascular treatments for acute ischemic stroke have shown promising results, indicating that this approach is supported by existing evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of acute ischemic stroke * Eligible for intravenous thrombolysis (IVT) and IVT initiated within 4.5 hours after stroke onset * Confirmed diagnosis of persistent occlusion of terminal carotid artery, middle cerebral artery (M1 or M2), or basilar artery consistent with symptoms * Age \>18 years * Ethic approval in process Exclusion Criteria: none
Where it's running
-
University Medical Center Hamburg-Eppendorf (UKE)
Hamburg, Free and Hanseatic City of Hamburg, Germany Recruiting
Study contacts
- Principal investigator: Martin Dichgans, Prof. Dr. med. — LMU, Munich, Germany
- Study coordinator: Maximilian Schell
- Email: m.schell@uke.de
- Phone: +49 (0)1522/2834807
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Short-Term outside-in nerve stimulation for acute ischemic stroke
This trial tests whether a 5-day external trigeminal nerve stimulation given after stroke can help more patients recover better than a sham treatment.
-
Sevoflurane vs. Propofol for anesthesia in stroke patients undergoing clot-removal
This study tests whether sevoflurane or propofol used for anesthesia during endovascular treatment of an acute ischemic stroke affects the final brain damage and recovery.
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Safety of adding NRICM301 to standard care for adults with acute ischemic stroke
This study tests whether adding NRICM301, a traditional Chinese medicine formula, to usual care is safe for adults with acute ischemic stroke.
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Intracranial Recanalization with LT3001 in Acute Ischemic Stroke
This phase II study tests whether LT3001 given to adults with acute ischemic stroke can help reopen blocked brain arteries.
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Mobilisation After Endovascular Stroke Treatment
This study checks whether moving around 12 hours after endovascular stroke treatment is as safe as moving around 24 hours for people with an acute ischemic stroke.
-
Endovascular therapy plus standard care vs standard care alone for distal and medium vessel strokes
In people with acute ischemic stroke due to distal or medium vessel blockages, this study tests whether adding endovascular treatment to the usual medical care helps improve outcomes compared with medical care alone.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.