Registry for Early Onset Hereditary Spastic Paraplegia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study gathers clinical data and biological samples from patients under 30 years old who have early onset hereditary spastic paraplegia (HSP) or are related to someone with the condition. The goal is to document the clinical presentation and natural history of HSP, facilitating early diagnosis and better family counseling. By collecting samples, the study aims to identify biomarkers and potential therapeutic targets for future treatments. The data will be stored securely and made available to researchers worldwide to advance understanding of HSP.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Onset of hereditary spastic paraplegia symptoms before the age of 18 years
* Under the age of 30 years old
* Must have a genetically confirmed variant in HSP-related genes and a relative of an individual with a confirmed diagnosis (if applicable).

Exclusion Criteria:

* Not having such a diagnosis and/or not being related to such individual

Where it's running

• Boston Children's Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Study coordinator: Darius Ebrahimi-Fakhari, MD, PhD
• Email: hsp.research@childrens.harvard.edu
• Phone: 617-355-6388

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Evaluating surgical treatment for foot deformities in hereditary spastic paraplegia

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.