Registry for chronic low back pain and healthy controls
Official title: Pain Registry for Epidemiological, Clinical, and Interventional Studies and Innovation
Run by University of North Texas Health Science Center · NCT04853732 · Data updated 2026-11-12
This study is trying to learn more about chronic low back pain by comparing people who have it with those who don’t, to see how pain affects their lives and what treatments work best.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 21 Years to 79 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | University of North Texas Health Science Center Academic / other |
| Locations | 1 site (Fort Worth, Texas) |
| Status | Recruiting |
| Started | April 2016 |
| Main results expected | December 2030 |
| Study ends | December 2030 |
| Registry record updated | January 16, 2024 |
| Trial ID | NCT04853732 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals residing in the contiguous 48 United States or District of Columbia with chronic low back pain or healthy volunteers without chronic pain.
✕Probably not a fit
Patients who are pregnant or residing in institutional facilities may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The PRECISION Pain Research Registry enrolls individuals with chronic low back pain and those without chronic pain to investigate the epidemiology and management of chronic pain. Participants complete various validated questionnaires at scheduled encounters to gather comprehensive data on their pain experiences and treatment approaches. The registry also collects biological specimens for future research on potential biomarkers related to chronic pain. This observational study aims to enhance understanding and improve management strategies for chronic low back pain.
Why it matters
Potential benefit: If successful, this registry could lead to improved treatment options and management strategies for individuals suffering from chronic low back pain.
How similar studies have gone: Other studies have shown success in utilizing similar observational approaches to understand chronic pain, making this registry a valuable addition to existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Must reside within the contiguous 48 United States or District of Columbia * Must provide a valid, government-issued identification with photo and birthdate * Must have Internet access or telephone service to communicate with registry staff * Must have sufficient English language proficiency to complete case report forms independently or with assistance from registry staff * Must have a primary care physician or other physician who regularly provides health care * Must provide the name, dose, and frequency of use of all current medications * Case participants must have chronic low back pain * Control participants must be free of any chronic pain and may include healthy volunteers Exclusion Criteria: * Must not be pregnant * Must not reside in an institutional facility
Where it's running
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University of North Texas Health Science Center
Fort Worth, Texas, United States Recruiting
Study contacts
- Principal investigator: John C Licciardone, DO, MS, MBA — University of North Texas Health Science Center
- Study coordinator: Cathleen Kearns, BA
- Email: orcstudyoperations@unthsc.edu
- Phone: 817-735-0515
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Ultrasound-Guided Thoracolumbar Fascia Injection for Chronic Low Back Pain in Type 2 Diabetes
This trial tests whether an ultrasound-guided injection into the thoracolumbar fascia, added to standard care, helps reduce chronic low back pain in adults with type 2 diabetes.
-
Subcutaneous Fat, Back Muscles, and Spine Shape in Back Pain Patients
This study tests whether body fat under the skin and features of back muscles and spine joints are linked to lumbar facet joint degeneration in adults with chronic low back pain.
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See if serum BDNF levels relate to outcomes in chronic low back pain
This study tests whether blood BDNF levels can help predict how patients with chronic low back pain will do over time.
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Correlating periostin levels with spinal degeneration in back pain
This study tests whether periostin levels in the intervertebral disc relate to the severity of disc degeneration in people with chronic low back pain and spinal stenosis.
-
Palmitoylethanolamide for Central Sensitisation and Neuroinflammation in Chronic Low Back Pain
A treatment with palmitoylethanolamide is being tried to see if it helps people with chronic low back pain who have nerve-related pain and disc problems.
-
Multichannel neuromuscular stimulation plus core exercise for chronic low back pain
This study tests two multichannel neuromuscular electrical stimulation programs added to a core exercise plan to see if they help adults with chronic non-specific low back pain.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.