Registry for Basal Joint Arthritis Treatments
Official title: Prospective Study on Basal Joint Arthritis of the Thumb
Run by Columbia University · NCT01376024 · Data updated 2026-11-12
This study is collecting information to see which treatments work best for people with thumb arthritis, helping to find the most effective ways to relieve pain and improve function.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | Columbia University Academic / other |
| Locations | 3 sites (Rochester, Minnesota and 2 other locations) |
| Status | Recruiting |
| Started | March 2, 2007 |
| Main results expected | February 2027 |
| Study ends | February 2027 |
| Registry record updated | June 10, 2026 |
| Trial ID | NCT01376024 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults with symptomatic basal joint arthritis who can provide informed consent.
✕Probably not a fit
Patients with inflammatory arthritic conditions or those unable to comply with study guidelines may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational registry aims to collect data on the effectiveness of various surgical and non-operative techniques for treating basal joint arthritis of the thumb. By analyzing patient-specific characteristics and treatment outcomes, the study seeks to identify the most effective and cost-efficient methods for pain relief and functional restoration. The findings will also help shape future randomized controlled trials focused on optimal treatment strategies for this condition. No interventions will be made to patient care during the study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and better patient outcomes for those suffering from basal joint arthritis.
How similar studies have gone: While there have been few multi-center prospective trials on this topic, the study builds on existing meta-analyses and aims to fill gaps in current knowledge.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who have symptomatic basal joint arthritis. * Patients who are capable of providing informed consent. Exclusion Criteria: * Patients younger than 18 years old at the time of enrollment. * Patients with neuromuscular disease affecting the operated hand, not caused by the CMC operation. * Patients with known inflammatory arthritic conditions, such as rheumatoid or psoriatic arthritis. * Patients with a history of or current infection of the basal joint of the affected hand. * Patients who are demented or are unable to provide informed consent. * Patients unable to comply with study guidelines. * Patients who have metacarpophalangeal joint hyperextension are NOT excluded. These patients will be followed and if they receive a capsulodesis or other procedure at the MCPJ at the same time as their basal joint arthroplasty this will be noted in their data records.
Where it's running
-
Columbia University/NY Presbyterian Hospital
New York, New York, United States Recruiting -
Mayo Clinic
Rochester, Minnesota, United States Terminated -
Vanderbilt University Hospital
Nashville, Tennessee, United States Terminated
Study contacts
- Principal investigator: Melvin P Rosenwasser, MD — Columbia University
- Study coordinator: Melvin P Rosenwasser, MD
- Email: mpr2@cumc.columbia.edu
- Phone: 212 305 8036
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Thumb base arthritis: joint replacement vs trapeziectomy
This trial tests whether a total thumb joint replacement (TOUCH prosthesis) works as well as trapeziectomy for people with basal thumb arthritis.
-
Touch CMC 1 Thumb Joint Replacement in US: New Enrollment Observational Study
This US post-approval study tests how well the TOUCH CMC 1 prosthesis works and stays safe for people with thumb base arthritis who need a first CMC joint replacement.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.