Registry for Basal Joint Arthritis Treatments
Multicenter Prospective Study on Basal Joint Arthritis of the Thumb
This study is collecting information to see which treatments work best for people with thumb arthritis, helping to find the most effective ways to relieve pain and improve function.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Columbia University Academic / other |
| Locations | 3 sites (Rochester, Minnesota and 2 other locations) |
| Trial ID | NCT01376024 on ClinicalTrials.gov |
What this trial studies
This observational registry aims to collect data on the effectiveness of various surgical and non-operative techniques for treating basal joint arthritis of the thumb. By analyzing patient-specific characteristics and treatment outcomes, the study seeks to identify the most effective and cost-efficient methods for pain relief and functional restoration. The findings will also help shape future randomized controlled trials focused on optimal treatment strategies for this condition. No interventions will be made to patient care during the study.
Who should consider this trial
Good fit: Ideal candidates include adults with symptomatic basal joint arthritis who can provide informed consent.
Not a fit: Patients with inflammatory arthritic conditions or those unable to comply with study guidelines may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and better patient outcomes for those suffering from basal joint arthritis.
How similar studies have performed: While there have been few multi-center prospective trials on this topic, the study builds on existing meta-analyses and aims to fill gaps in current knowledge.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who have symptomatic basal joint arthritis. * Patients who are capable of providing informed consent. Exclusion Criteria: * Patients younger than 18 years old at the time of enrollment. * Patients with neuromuscular disease affecting the operated hand, not caused by the CMC operation. * Patients with known inflammatory arthritic conditions, such as rheumatoid or psoriatic arthritis. * Patients with a history of or current infection of the basal joint of the affected hand. * Patients who are demented or are unable to provide informed consent. * Patients unable to comply with study guidelines. * Patients who have metacarpophalangeal joint hyperextension are NOT excluded. These patients will be followed and if they receive a capsulodesis or other procedure at the MCPJ at the same time as their basal joint arthroplasty this will be noted in their data records.
Where this trial is running
Rochester, Minnesota and 2 other locations
- Mayo Clinic — Rochester, Minnesota, United States (Recruiting)
- Columbia University/NY Presbyterian Hospital — New York, New York, United States (Recruiting)
- Vanderbilt University Hospital — Nashville, Tennessee, United States (Recruiting)
Study contacts
- Principal investigator: Melvin P Rosenwasser, MD — Columbia University
- Study coordinator: Bryanna Geiger
- Email: bg2603@columbia.edu
- Phone: 212-305-3912
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.