Clinical trial Recruiting at 1 site Observational

Registry analyzing spontaneous coronary artery dissection in Brazil

Official title: Spontaneous Coronary Artery Dissection anaLysIs of the Brazilian Updated Registry: Epidemiological Data, Clinical Results and Long-Term Follow-up (SCALIBUR Registry).

Run by Hospital Israelita Albert Einstein · NCT03398850 · Data updated 2026-11-12

This study looks at patients in Brazil with spontaneous coronary artery dissection to see how they are treated and to gather information about their health over time.

Quick facts

Study typeObservational
SexAll
Enrollment250 (estimated)
SponsorHospital Israelita Albert Einstein
Academic / other
Locations1 site (São Paulo, São Paulo)
StatusRecruiting
StartedJanuary 1, 2000
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedJanuary 17, 2018
Trial IDNCT03398850 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients diagnosed with spontaneous coronary artery dissection who have angiographic confirmation of the condition.

Probably not a fit

Patients with coronary dissections caused by other mechanisms, such as unstable atherosclerotic plaque or trauma, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry aims to evaluate both retrospective and prospective data on patients diagnosed with spontaneous coronary artery dissection (SCAD). It will collect demographic and angiographic information through medical records, invasive coronary angiography, and computed multislice coronary tomography. The study will also assess the treatment approaches used during initial hospitalization, including clinical management, percutaneous coronary intervention, or coronary artery bypass grafting, and will provide long-term follow-up data for up to 10 years.

Why it matters

Potential benefit: If successful, this study could enhance understanding of SCAD and improve treatment strategies for affected patients.

How similar studies have gone: While there have been studies on SCAD, this registry approach focusing on long-term outcomes and treatment strategies is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with coronary manifestations due spontaneous coronary artery dissection
* Angiographic findings of SCAD in coronary angiogram or coronary tomography
* Agreement between two or more invasive cardiologists (adjudicated committee) for the diagnosis.

Exclusion Criteria:

* Non-agreement for SCAD diagnosis
* Coronary dissections due other mechanisms: unstable atherosclerotic plaque or trauma-induced.

Where it's running

  • Hospital Israelita Albert Einstein
    São Paulo, São Paulo, Brazil
    Recruiting

Study contacts

  • Principal investigator: Jamil Cade, MD, PhD — Hospital Israelita Albert Einstein
  • Study coordinator: Carolina Pereira, RN
  • Email: carolinap@einstein.br
  • Phone: +551121519408

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.