Registry analyzing spontaneous coronary artery dissection in Brazil
Spontaneous Coronary Artery Dissection anaLysIs of the Brazilian Updated Registry: Epidemiological Data, Clinical Results and Long-Term Follow-up (SCALIBUR Registry).
This study looks at patients in Brazil with spontaneous coronary artery dissection to see how they are treated and to gather information about their health over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Sex | All |
| Sponsor | Hospital Israelita Albert Einstein Academic / other |
| Locations | 1 site (São Paulo, São Paulo) |
| Trial ID | NCT03398850 on ClinicalTrials.gov |
What this trial studies
This observational registry aims to evaluate both retrospective and prospective data on patients diagnosed with spontaneous coronary artery dissection (SCAD). It will collect demographic and angiographic information through medical records, invasive coronary angiography, and computed multislice coronary tomography. The study will also assess the treatment approaches used during initial hospitalization, including clinical management, percutaneous coronary intervention, or coronary artery bypass grafting, and will provide long-term follow-up data for up to 10 years.
Who should consider this trial
Good fit: Ideal candidates include patients diagnosed with spontaneous coronary artery dissection who have angiographic confirmation of the condition.
Not a fit: Patients with coronary dissections caused by other mechanisms, such as unstable atherosclerotic plaque or trauma, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of SCAD and improve treatment strategies for affected patients.
How similar studies have performed: While there have been studies on SCAD, this registry approach focusing on long-term outcomes and treatment strategies is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with coronary manifestations due spontaneous coronary artery dissection * Angiographic findings of SCAD in coronary angiogram or coronary tomography * Agreement between two or more invasive cardiologists (adjudicated committee) for the diagnosis. Exclusion Criteria: * Non-agreement for SCAD diagnosis * Coronary dissections due other mechanisms: unstable atherosclerotic plaque or trauma-induced.
Where this trial is running
São Paulo, São Paulo
- Hospital Israelita Albert Einstein — São Paulo, São Paulo, Brazil (Recruiting)
Study contacts
- Principal investigator: Jamil Cade, MD, PhD — Hospital Israelita Albert Einstein
- Study coordinator: Carolina Pereira, RN
- Email: carolinap@einstein.br
- Phone: +551121519408
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.