Registry analyzing spontaneous coronary artery dissection in Brazil
Official title: Spontaneous Coronary Artery Dissection anaLysIs of the Brazilian Updated Registry: Epidemiological Data, Clinical Results and Long-Term Follow-up (SCALIBUR Registry).
Run by Hospital Israelita Albert Einstein · NCT03398850 · Data updated 2026-11-12
This study looks at patients in Brazil with spontaneous coronary artery dissection to see how they are treated and to gather information about their health over time.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | Hospital Israelita Albert Einstein Academic / other |
| Locations | 1 site (São Paulo, São Paulo) |
| Status | Recruiting |
| Started | January 1, 2000 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | January 17, 2018 |
| Trial ID | NCT03398850 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with spontaneous coronary artery dissection who have angiographic confirmation of the condition.
✕Probably not a fit
Patients with coronary dissections caused by other mechanisms, such as unstable atherosclerotic plaque or trauma, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational registry aims to evaluate both retrospective and prospective data on patients diagnosed with spontaneous coronary artery dissection (SCAD). It will collect demographic and angiographic information through medical records, invasive coronary angiography, and computed multislice coronary tomography. The study will also assess the treatment approaches used during initial hospitalization, including clinical management, percutaneous coronary intervention, or coronary artery bypass grafting, and will provide long-term follow-up data for up to 10 years.
Why it matters
Potential benefit: If successful, this study could enhance understanding of SCAD and improve treatment strategies for affected patients.
How similar studies have gone: While there have been studies on SCAD, this registry approach focusing on long-term outcomes and treatment strategies is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with coronary manifestations due spontaneous coronary artery dissection * Angiographic findings of SCAD in coronary angiogram or coronary tomography * Agreement between two or more invasive cardiologists (adjudicated committee) for the diagnosis. Exclusion Criteria: * Non-agreement for SCAD diagnosis * Coronary dissections due other mechanisms: unstable atherosclerotic plaque or trauma-induced.
Where it's running
-
Hospital Israelita Albert Einstein
São Paulo, São Paulo, Brazil Recruiting
Study contacts
- Principal investigator: Jamil Cade, MD, PhD — Hospital Israelita Albert Einstein
- Study coordinator: Carolina Pereira, RN
- Email: carolinap@einstein.br
- Phone: +551121519408
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.