Reducing ventilator-associated pneumonia in newborns in the NICU

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The project implements a multicenter, quasi-experimental observational program to standardize definitions, diagnosis, and prevention of ventilator-associated pneumonia in neonatal intensive care units. Participating units receive training on a multimodal bundle of evidence-based practices (oral care, suctioning, patient positioning, protected catheter techniques, and related protocols). A prospective surveillance registry will collect demographic, clinical, and ventilation-related data for infants on invasive mechanical ventilation to measure incidence before and after the intervention. The aim is to harmonize practice across sites and measure whether the intervention reduces VAP frequency and impact.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients admitted to participating NICUs who are in IMV for at least 48 hours, regardless of birth weight, gestational age or medical condition.

Exclusion Criteria:

* Patients who remain in IMV less than 48 hours.
* Decision of the healthcare professional in charge of the patient's treatment to exclude their participation at any moment due to the considerations of necessity.

Where it's running

• Hospital Universitario de A Coruña
  A Coruña, A Coruña, Spain Recruiting
• Complejo Hospitalario Universitario de Albacete
  Albacete, Albacete, Spain Recruiting
• Hospital Universitario Germans Trias i Pujol
  Badalona, Barcelona, Spain Recruiting
• Hospital de la Santa Creu i Sant Pau
  Barcelona, Barcelona, Spain Recruiting
• Hospital Universitario Vall d'Hebrón
  Barcelona, Barcelona, Spain Recruiting
• Hospital Universitario de Cruces
  Barakaldo, Bizkaia, Spain Recruiting

Study contacts

• Study coordinator: Patricia Sanchez Hernandez
• Email: patricia.sanchezhernandez@bio-bizkaia.eus
• Phone: 946006136

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Ventilator-associated pneumonia rates and use of SRLF 2017 diagnostic rules in an ICU (2022–2024)

  This project will look at respiratory samples from adults on mechanical ventilation in a regional ICU to see if doctors followed the SRLF 2017 rules when diagnosing ventilator-associated pneumonia between 2022 and 2024.

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• Antibiotic approaches for Stenotrophomonas maltophilia pneumonia in ICU patients

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• Program to improve hand hygiene and reduce infections in hospitals

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  Recruiting Centro Cardiologico Monzino · Milan, Italy · NCT06857825

• Examining immunity markers in ICU patients with ventilator-associated pneumonia

  This study is trying to see if measuring certain immune markers in ICU patients with ventilator-associated pneumonia can help improve their treatment and outcomes.

  Recruiting Centre Hospitalier Intercommunal Aix-Pertuis · Aix-en-Provence · NCT06607055

• Using sequencing to predict outcomes of pneumonia in ventilated patients

  This study is testing if analyzing germs in the lungs of patients on ventilators can help predict how well they will recover from pneumonia.

  Recruiting The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT06467864

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.