Reducing unnecessary medications for overactive bladder in older adults
Deprescribing DRugs for Overactive Bladder in the Elderly in General Practice - a Randomized Controlled Trial with a Nested Mixed Methods Study
This study tests whether reducing unnecessary medications for overactive bladder can help older adults feel better and avoid side effects.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 65 Years to 95 Years |
| Sex | All |
| Sponsor | Aalborg University Hospital Academic / other |
| Locations | 1 site (Aalborg) |
| Trial ID | NCT06110975 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of a deprescribing intervention in primary care for older adults with overactive bladder. It focuses on reducing potentially inappropriate medications, particularly anticholinergic drugs, which may have unfavorable risk-benefit profiles. The study employs a mixed methods explanatory sequential design, combining a randomized controlled trial with qualitative insights from general practitioners, support staff, and patients. By comparing an intervention group to a control group, the study aims to gather comprehensive data on the deprescribing process and its outcomes.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 65 or older who have been prescribed medications for overactive bladder within the last 14 months and can communicate in Danish.
Not a fit: Patients who are cognitively impaired or receiving specialized neurological or urogenital care for their overactive bladder symptoms may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could lead to safer and more effective medication regimens for older adults suffering from overactive bladder.
How similar studies have performed: Other studies have shown promise in deprescribing interventions for older adults, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patient must have been prescribed one of the following drugs for OAB within the last 14 months * patient must be able to speak and understand Danish Exclusion Criteria: * too cognitively impaired to participate or otherwise unfit to participate as estimated by general practitioner * receiving neurological or urogenital ambulatory care for their overactive bladder symptoms
Where this trial is running
Aalborg
- Aalborg University Hospital — Aalborg, Denmark (Recruiting)
Study contacts
- Principal investigator: Anne E Olesen, Professor — Aalborg University Hospital
- Study coordinator: Anne E Olesen, Professor
- Email: aneso@rn.dk
- Phone: 0045 2628 1305
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.