Reducing post-mastectomy pain with opioid-free anesthesia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study involves 230 patients undergoing mastectomy, where participants will be randomly assigned to receive either opioid-free anesthesia or conventional opioid-based anesthesia. The aim is to compare the effectiveness of these two approaches in reducing chronic pain one year after surgery. Pain assessments will be conducted using various questionnaires and tests to evaluate pain sensitivity and psychological factors before and after the procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All of patients will undergo mastectomy with or without immediate breast reconstruction.

Exclusion Criteria:

* Previous history of breast surgery
* Allergy to drug
* Other cancer history
* Underlying psychologic disorder
* Patients with chronic pain requiring pain killers
* Baseline SpO2 \<95%
* Left ventricular EF \<40%
* Bradycardia as HR \<50 bpm
* BMI \>35kg/m2
* Pregnant woman

Where it's running

• Gangnam Severance Hospital
  Seoul, South Korea Recruiting

Study contacts

• Principal investigator: Sung Gwe G Ahn, M.D.,Ph.D. — Gangnam Severance Hospital
• Study coordinator: Sung Gwe Ahn, M.D.,Ph.D.
• Email: asg2004@yuhs.ac
• Phone: 82220194402

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Opioid-free anesthesia for breast cancer surgery

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.