Rectal cancer registry to track real-world treatments and outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry gathers routine-care information from about 600 adults treated at roughly six Austrian sites. It focuses on locally advanced rectal adenocarcinoma, documenting treatment approaches—especially total neoadjuvant therapy—and disease status by microsatellite condition (dMMR/MSI-H). Data come from standard clinical care without altering treatment decisions, and both retrospective and prospective participants are included. The study aims to characterize variability in practice and associated outcomes across institutions. No interventional procedures are required beyond usual care, and participation does not change treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female and male participants with age \>= 18 years
* Signed informed consent obtained prior to registration of the participant.
* Localized rectal cancer treated with TNT or localized, non-metastatic dMMR/MSI-H rectal cancer, irrespective of treatment

Exclusion Criteria:

* Distant metastases at primary diagnosis

Where it's running

• LKH Salzburg-PMU, Univ. Klinik f. Innere Med III
  Salzburg, State of Salzburg, Austria Recruiting
• Kepler Universitätsklinikum Linz
  Linz, Upper Austria, Austria Recruiting
• Universitätsklinikum Wiener Neustadt, Abteilung für Innere Medizin, Hämatologie und int. Onkologie
  Wiener Neustadt, Lower Austria, Austria Not yet recruiting
• Med. University Graz, Oncology
  Graz, Styria, Austria Not yet recruiting
• Medical University Innsbruck, Internal Medicine V
  Innsbruck, Tyrol, Austria Not yet recruiting
• Ordensklinikum Linz - BHS
  Linz, Upper Austria, Austria Not yet recruiting

Study contacts

• Study coordinator: Miriam Muehlburger, MSc
• Email: miriam.muehlburger@abcsg.at
• Phone: +43 1 4089230

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.