Real-time notifications during colonoscopy to reduce patient anxiety and depression

Impact of Real-time Notification of Colonoscopic Optical Diagnosis on Patients' Anxiety and Depression After Polypectomy: a Randomized Control Trial

Not applicable Interventional Fu Jen Catholic University · NCT05517343

This study is testing if giving patients real-time updates about their colorectal polyps during a colonoscopy can help reduce their anxiety and depression after the procedure.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment500 (estimated)
Ages40 Years to 79 Years
SexAll
SponsorFu Jen Catholic University Academic / other
Locations1 site (New Taipei City)
Trial IDNCT05517343 on ClinicalTrials.gov

What this trial studies

This study investigates the effect of real-time notifications regarding the nature of colorectal polyps on patients' anxiety and depression levels after polypectomy. It is a single-center, open-label, prospective, and parallel randomized controlled trial involving outpatients aged 40 to 79 scheduled for sedated colonoscopy. Participants diagnosed with colorectal polyps will be randomly assigned to either receive immediate feedback about their diagnosis or standard care, with their anxiety and depression levels measured before their next clinic visit for histological results. The goal is to determine if real-time notifications can improve post-polypectomy care and enhance patients' quality of life.

Who should consider this trial

Good fit: Ideal candidates are outpatients aged 40 to 79 who are scheduled for sedated colonoscopy and are expected to undergo polypectomy.

Not a fit: Patients with major mental illnesses or contraindications to colonoscopy may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce anxiety and depression in patients undergoing polypectomy.

How similar studies have performed: While similar studies have explored patient anxiety in medical procedures, this specific approach of real-time notifications is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age of ≥ 40 years and \< 80 years
* Outpatients who prepare receiving sedated colonoscopy
* Subjects who have signed informed consent form of this study
* Informed consensus has been obtained that endoscopic resection should be performed if a colorectal polyp is found
* Eastern Cooperative Oncology Group (ECOG) performance status scale among 0 to 2

Exclusion Criteria:

* Subjects with any of the following prior history or current conditions:
* (a) Contraindications to colonoscopy
* (b) Major mental illnesses, e.g. major depressive disorder, schizophrenia, generalized anxiety disorder ...
* (c) Inflammatory bowel disease
* (d) Hereditary or non-hereditary polyposis syndrome, hereditary non-polyposis colorectal cancer
* (e) Uncured colorectal cancer
* (f) Active gastrointestinal bleeding
* (g) Pregnancy
* Subjects who do not received polypectomy during colonoscopy.

Where this trial is running

New Taipei City

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Colorectal NeoplasmsColonic PolypAnxietyDepressionColonoscopycolonoscopypolypectomyimage enhanced endoscopy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.