Readiness for EXtubation (REXs) score for patients on invasive mechanical ventilation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational, multi-center study aims to develop and validate a multi-component Readiness for EXtubation (REXs) score using clinical parameters and spontaneous breathing trial results in patients undergoing weaning from invasive mechanical ventilation. The score will be derived and calibrated across participating ICUs, with extubation success defined as not requiring invasive mechanical support within 48 hours. Standard inclusion and exclusion criteria will be applied and sites will report findings following the STROBE guidance. Collected data will be used to test predictive performance and optimize score thresholds before broader validation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Patients who are in the weaning process from mechanical ventilation after being connected to invasive mechanical ventilation in the intensive care unit.

Exclusion Criteria:

* Patients without legal guardian consent.
* Tracheostomized patients.
* Patients enrolled in other studies.
* Individuals with diaphragmatic pacers.
* Pregnant patients.

Where it's running

• University of Magallanes
  Punta Arenas, Chile Recruiting
• Cairo University
  Cairo, Egypt Recruiting
• Shahid Beheshti University of Medical Sciences
  Tehran, Iran Recruiting
• A.O.R.N. "Dei Colli" Monaldi Hospital
  Naples, Italy Recruiting
• Monaldi-Cotugno Hospital
  Naples, Italy Recruiting
• Hospital General Universitario Morales Meseguer
  Murcia, Spain Recruiting

Study contacts

• Study coordinator: Berkan Basançelebi
• Email: berkan.basancelebi@medipol.edu.tr
• Phone: +90 444 8 544

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.