Rapid blood test using GFAP to tell hemorrhagic vs ischemic stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort will enroll adults with suspected stroke who present within three hours and collect peripheral blood to measure GFAP and other biomarkers. The project partners hospitals with industry to develop and validate a rapid diagnostic workflow aimed at pre-hospital and emergency use. Results will be compared to clinical imaging to determine how well the biomarker distinguishes intracerebral hemorrhage from ischemic stroke. The goal is to produce data that could support faster, guided treatment decisions in the ambulance or emergency department.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 years old;
2. Suspected stroke at emergency department arrival (FAST score ≥ 2 points, must include limb weakness);
3. Time of stroke symptom onset/last known normal within 3 hours.

Exclusion Criteria:

1. Coma - no response to tactile or verbal stimuli;
2. Severe comorbidities (such as tumors, severe COPD, severe heart failure, requiring assistance with daily living \[unable to walk independently\]);
3. History of epilepsy or onset with seizure;
4. Recent history of head trauma (\< 7 days);
5. Blood glucose \< 2.8 mmol/L.

Where it's running

• Shanghai East Hospital
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Gang Li
• Email: ligang@tongji.edu.cn
• Phone: +86 136 2169 1786

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

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• Dual-task balance training plus computer-based cognitive training after stroke

  In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.

  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.