Radiofrequency ablation for chronic pain after knee surgery

Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain. A Randomized Double-blind Study. A Novel Approach.

Not applicable Interventional Consorci Sanitari de l'Alt Penedès i Garraf · NCT05920382

This study tests whether a treatment called radiofrequency ablation can help people with ongoing knee pain after knee surgery feel better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment86 (estimated)
Ages18 Years and up
SexAll
SponsorConsorci Sanitari de l'Alt Penedès i Garraf Academic / other
Locations1 site (Barcelona, Catalonia)
Trial IDNCT05920382 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the use of radiofrequency ablation to treat chronic knee pain in patients who have undergone knee arthroplasty. The study focuses on individuals experiencing persistent pain for at least six months post-surgery, targeting specific sensory nerves that may contribute to their discomfort. By applying radiofrequency energy to these nerves, the trial aims to alleviate pain and improve the quality of life for affected patients. The methodology includes assessing pain intensity and stability prior to treatment to ensure appropriate candidate selection.

Who should consider this trial

Good fit: Ideal candidates are individuals who have had knee arthroplasty and experience chronic knee pain rated at 5 or higher on a pain scale for at least six months.

Not a fit: Patients with acute knee pain, psychiatric disorders, or those who have received recent corticosteroid injections will not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly reduce chronic pain and improve the quality of life for patients suffering after knee arthroplasty.

How similar studies have performed: While radiofrequency ablation has been used for chronic pain management, the specific application for post-knee arthroplasty pain is less established and may represent a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals who have undergone knee arthroplasty.
* Chronic knee pain post-knee arthroplasty for at least 6 months after the procedure and less than 5 years.
* Pain intensity on the numerical visual scale ≥ 5 out of 10 points.
* Stable pain for the last 30 days.
* The knee is the location with the highest intensity of pain, in the case of patients with multiple joint pains.

Exclusion Criteria:

* Acute knee pain.
* Psychiatric illness or dementia that may interfere with or hinder study assessments.
* Diagnosis of fibromyalgia, chronic fatigue syndrome, or central sensitization syndrome.
* Knee infiltration with corticosteroids in the past 30 days.
* Changes in oral analgesic medication in the past 30 days.

Where this trial is running

Barcelona, Catalonia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Post-surgical PainChronic Post Operative PainChronic Knee Pain
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.