Radiofrequency ablation for chronic pain after knee surgery
Official title: Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain. A Randomized Double-blind Study. A Novel Approach.
Run by Consorci Sanitari de l'Alt Penedès i Garraf · NCT05920382 · Data updated 2026-11-12
This study tests whether a treatment called radiofrequency ablation can help people with ongoing knee pain after knee surgery feel better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 86 (estimated) |
| Sponsor | Consorci Sanitari de l'Alt Penedès i Garraf Academic / other |
| Locations | 1 site (Barcelona, Catalonia) |
| Status | Recruiting |
| Started | September 25, 2023 |
| Main results expected | September 1, 2027 |
| Study ends | December 1, 2028 |
| Registry record updated | October 30, 2026 |
| Trial ID | NCT05920382 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals who have had knee arthroplasty and experience chronic knee pain rated at 5 or higher on a pain scale for at least six months.
✕Probably not a fit
Patients with acute knee pain, psychiatric disorders, or those who have received recent corticosteroid injections will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the use of radiofrequency ablation to treat chronic knee pain in patients who have undergone knee arthroplasty. The study focuses on individuals experiencing persistent pain for at least six months post-surgery, targeting specific sensory nerves that may contribute to their discomfort. By applying radiofrequency energy to these nerves, the trial aims to alleviate pain and improve the quality of life for affected patients. The methodology includes assessing pain intensity and stability prior to treatment to ensure appropriate candidate selection.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce chronic pain and improve the quality of life for patients suffering after knee arthroplasty.
How similar studies have gone: While radiofrequency ablation has been used for chronic pain management, the specific application for post-knee arthroplasty pain is less established and may represent a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals who have undergone knee arthroplasty. * Chronic knee pain post-knee arthroplasty for at least 6 months after the procedure and less than 5 years. * Pain intensity on the numerical visual scale ≥ 5 out of 10 points. * Stable pain for the last 30 days. * The knee is the location with the highest intensity of pain, in the case of patients with multiple joint pains. Exclusion Criteria: * Acute knee pain. * Psychiatric illness or dementia that may interfere with or hinder study assessments. * Diagnosis of fibromyalgia, chronic fatigue syndrome, or central sensitization syndrome. * Knee infiltration with corticosteroids in the past 30 days. * Changes in oral analgesic medication in the past 30 days.
Where it's running
-
Consorci Sanitari Alt'Pènedes i Garraf
Barcelona, Catalonia, Spain Recruiting
Study contacts
- Study coordinator: Italo G Pisani, Md
- Email: italopisani1976@gmail.com
- Phone: +34649034623
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.