Quality of life intervention for young African American breast cancer survivors

Piloting Y-AMBIENT: A Quality of Life Intervention for Young African American Breast Cancer Survivors in Treatment

Not applicable Interventional University of Alabama at Birmingham · NCT05243056

This study is testing a phone program to see if it can help improve the quality of life for young African American women who have been diagnosed with breast cancer.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 44 Years
SexFemale
SponsorUniversity of Alabama at Birmingham Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Columbus, Ohio)
Trial IDNCT05243056 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the Y-AMBIENT intervention, a four-month telephone-based program designed to improve the quality of life for young African American women diagnosed with stage I-III breast cancer. Participants are randomized into two groups: one receiving the Y-AMBIENT intervention, which includes themed education sessions and follow-up calls, and the other receiving enhanced usual care. The study aims to assess the feasibility and acceptability of the intervention while exploring its impact on health-related outcomes. The trial is conducted by the University of Alabama at Birmingham in collaboration with the National Cancer Institute.

Who should consider this trial

Good fit: Ideal candidates are African American women aged 18 to 44 who are currently undergoing treatment for stage I-III breast cancer.

Not a fit: Patients who are already participating in formal survivorship navigation programs may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance the quality of life and health outcomes for young African American breast cancer survivors.

How similar studies have performed: Other studies have shown promising results with similar quality of life interventions, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Biologically born women
* Self-identify as AA
* Are aged 18 to 44 years on study entry
* Are diagnosed with breast cancer stage I-III
* Are in treatment with chemotherapy and/or radiation for stage I-III breast cancer at study entry
* Are English- speaking
* Have telephone and internet access

Exclusion Criteria:

* Participation in formal survivorship navigation programs because they are associated with improved health- related outcomes, which could be a confounder

Where this trial is running

Columbus, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage IA Breast Cancer AJCC v8Anatomic Stage IB Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIA Breast Cancer AJCC v8Anatomic Stage IIB Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.