Quality of life for people with glaucoma
Glaucoma Related Quality of Life
This project asks adults with glaucoma to complete vision-related questionnaires before and 3–6 months after starting treatment or having surgery to see if their scores change.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Iowa Academic / other |
| Locations | 1 site (Iowa City, Iowa) |
| Trial ID | NCT07510087 on ClinicalTrials.gov |
What this trial studies
Adults with open- or closed-angle glaucoma (primary or secondary) complete several validated questionnaires—GQL-15, Glaucoma Symptom Scale, NEI Visual Function Questionnaire, and Ocular Surface Disease Index—at baseline and again 3–6 months after initiating medical treatment or undergoing surgery. The protocol is observational and follows real-world care rather than assigning interventions. Data are collected at the University of Iowa Department of Ophthalmology & Visual Sciences and compared between baseline and follow-up time points. The goal is to characterize how different glaucoma treatments affect patient-reported vision-related quality of life over time.
Who should consider this trial
Good fit: Adults aged 18 and older with any form of glaucoma who are about to begin medical treatment or undergo glaucoma surgery.
Not a fit: People without a glaucoma diagnosis, under 18, or not undergoing new treatment or surgery are unlikely to gain information from participating.
Why it matters
Potential benefit: If successful, the results could help clinicians better understand how treatments and surgeries affect patients' daily vision and symptoms, informing care decisions to improve quality of life.
How similar studies have performed: Questionnaire-based studies using instruments like the NEI VFQ and GQL-15 have been used before to detect changes in vision-related quality of life in glaucoma, so this approach is well-established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion: * diagnosis of glaucoma (open- as well as closed-angle glaucoma, primary and secondary glaucomas) * 18 years of age or older with no upper limit * male and female subjects Exclusion: * absence of a diagnosis of glaucoma * less than 18 years of age
Where this trial is running
Iowa City, Iowa
- University of Iowa, Dept. of Ophthalmology & Visual Sciences — Iowa City, Iowa, United States (Recruiting)
Study contacts
- Study coordinator: Marc Toeteberg-Harms, MD
- Email: marc-toeteberg-harms@uiowa.edu
- Phone: +1 319 356 3938
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.