Clinical trial Recruiting at 1 site Observational Ages 18 and up

Quality of life for people with glaucoma

Official title: Glaucoma Related Quality of Life

Run by University of Iowa · NCT07510087 · Data updated 2026-11-12

This project asks adults with glaucoma to complete vision-related questionnaires before and 3–6 months after starting treatment or having surgery to see if their scores change.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorUniversity of Iowa
Academic / other
Locations1 site (Iowa City, Iowa)
StatusRecruiting
StartedDecember 30, 2024
Main results expectedNovember 30, 2026
Study endsMay 30, 2027
Registry record updatedApril 6, 2026
Trial IDNCT07510087 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 and older with any form of glaucoma who are about to begin medical treatment or undergo glaucoma surgery.

Probably not a fit

People without a glaucoma diagnosis, under 18, or not undergoing new treatment or surgery are unlikely to gain information from participating.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with open- or closed-angle glaucoma (primary or secondary) complete several validated questionnaires—GQL-15, Glaucoma Symptom Scale, NEI Visual Function Questionnaire, and Ocular Surface Disease Index—at baseline and again 3–6 months after initiating medical treatment or undergoing surgery. The protocol is observational and follows real-world care rather than assigning interventions. Data are collected at the University of Iowa Department of Ophthalmology & Visual Sciences and compared between baseline and follow-up time points. The goal is to characterize how different glaucoma treatments affect patient-reported vision-related quality of life over time.

Why it matters

Potential benefit: If successful, the results could help clinicians better understand how treatments and surgeries affect patients' daily vision and symptoms, informing care decisions to improve quality of life.

How similar studies have gone: Questionnaire-based studies using instruments like the NEI VFQ and GQL-15 have been used before to detect changes in vision-related quality of life in glaucoma, so this approach is well-established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion:

* diagnosis of glaucoma (open- as well as closed-angle glaucoma, primary and secondary glaucomas)
* 18 years of age or older with no upper limit
* male and female subjects

Exclusion:

* absence of a diagnosis of glaucoma
* less than 18 years of age

Where it's running

  • University of Iowa, Dept. of Ophthalmology & Visual Sciences
    Iowa City, Iowa, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.