Quality of life and medication use after CAR-T treatment for diffuse large B‑cell lymphoma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, non-comparative observational study of adults with diffuse large B‑cell lymphoma treated with commercial CAR‑T cells at Hospices Civils de Lyon. Participants will complete self-administered questionnaires and take part in semi-structured interviews to document quality of life, real-world drug consumption, and patient experience. Data collection occurs during routine hematology follow-up and through the clinical pharmacy unit to capture real-life care outside clinical trials. The goal is to provide complementary real-world evidence to the pivotal phase 1–2 trials that focused mainly on efficacy and safety.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Over 18 years old
* Eligible for treatment with CAR-T cells (outside any clinical trial) in an indication of DLBCL and for which treatment is scheduled
* Follow-up in the Hematology department of the Hospices Civils de Lyon
* Without major psychiatric disorder likely to interfere with the conduct of the study, in the opinion of the investigator
* Having given his non-opposition to participate in the study.

Exclusion Criteria:

* In an institution
* Under legal protection

Where it's running

• Hospices Civils de Lyon -Groupement Hospitalier Sud Service pharmaceutique, Unité de Pharmacie Clinique Oncologique
  Pierre-Bénite, France Recruiting

Study contacts

• Study coordinator: Catherine RIOUFOL, Pharm. D
• Email: catherine.rioufol@chu-lyon.fr
• Phone: 04 78 86 43 70

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.