Quality of life after atrial fibrillation following heart surgery
Official title: Prospective Observational Study on Quality of Life With Postoperative Atrial Fibrillation
Run by Brigham and Women's Hospital · NCT07173998 · Data updated 2026-11-12
This project will see how atrial fibrillation that starts after heart surgery affects quality of life in adults having cardiac operations.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 260 (estimated) |
| Sponsor | Brigham and Women's Hospital Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | July 15, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | July 1, 2027 |
| Registry record updated | June 29, 2026 |
| Trial ID | NCT07173998 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–99 scheduled for non-emergent cardiac surgery who can complete surveys and do not have persistent or preoperative atrial fibrillation are ideal candidates.
✕Probably not a fit
People with persistent or preexisting atrial fibrillation, those presenting in atrial fibrillation before surgery, patients having emergent operations, or those unable to complete questionnaires are unlikely to benefit from this project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective observational project that follows adults scheduled for cardiac surgery who develop postoperative atrial fibrillation. Participants complete baseline surveys before surgery and follow-up surveys at one month and three months after the operation using the SF-36, TSQM-9, and open-ended questions. The design captures short-term changes in health-related quality of life and treatment satisfaction without introducing new treatments. Patients with persistent or preoperative atrial fibrillation and those undergoing emergent operations are excluded.
Why it matters
Potential benefit: If successful, the findings could help clinicians better understand recovery after postoperative atrial fibrillation and tailor follow-up care to improve patients' quality of life.
How similar studies have gone: Prior observational work links postoperative atrial fibrillation to worse short-term outcomes and reduced quality of life, but prospective surveys at 1 and 3 months are relatively limited, so this approach builds on but also fills gaps in existing evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All genders * Ages 18-99 years old * Scheduled to undergo cardiac surgery * Able to answer survey questions Exclusion Criteria: * Persistent / permanent atrial fibrillation * Atrial fibrillation at presentation for surgery * Emergent operations
Where it's running
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Mass General Brigham
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Jakob Wollborn, MD, MPH — Brigham and Women's Hospital
- Study coordinator: Leonard Simeth, cand.med.
- Email: lsimeth@bwh.harvard.edu
- Phone: +1 6173 529209
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Can short-term atorvastatin around surgery help prevent atrial fibrillation after lung surgery?
This trial tests whether giving a short course of atorvastatin around surgery can reduce new atrial fibrillation after lung resection in adults aged 60 and older.
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Using radiofrequency ablation to prevent atrial fibrillation after heart surgery
This study is testing if a special heart procedure can help prevent new cases of atrial fibrillation in patients after they have heart surgery.
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Smartwatch detection of atrial fibrillation after thoracic (lung) surgery
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Assessing right atrial strain to predict postoperative atrial fibrillation after heart surgery
This study is testing if measuring right atrial strain can help predict the risk of developing atrial fibrillation after heart surgery in adults.
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Using Atorvastatin to prevent postoperative atrial fibrillation in heart surgery patients
This study is testing if taking Atorvastatin before and after heart surgery can help prevent a common heart rhythm problem called atrial fibrillation in patients who are having their aortic valve replaced.
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Effects of Statins on Atrial Fibrillation After Aortic Valve Surgery
This study tests whether taking statins before and after aortic valve surgery can help prevent heart rhythm problems in patients undergoing the procedure.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.