Quadro-iliac versus thoracolumbar interfascial plane block for pain after single-level lumbar disc surgery
Comparison of the Postoperative Analgesic Efficacy of the Quadro-Iliac Plane Block and the Classical Thoracolumbar Interfascial Plane Block in Single-Level Lumbar Disc Surgery: A Prospective Randomized Controlled Trial
This trial tries two different regional nerve blocks to see which provides better pain relief after single-level lumbar disc surgery in adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Samsun University Academic / other |
| Locations | 1 site (Samsun) |
| Trial ID | NCT07348419 on ClinicalTrials.gov |
What this trial studies
Adults aged 18–70 scheduled for single-level lumbar spinal surgery under general anesthesia will receive either a classical thoracolumbar interfascial plane (TLIP) block or a Quadro-iliac plane block (QIPB) for postoperative analgesia. Both are ultrasound-guided interfascial regional techniques intended to reduce postoperative pain and opioid needs after extensive dissection. Investigators will compare postoperative pain scores, opioid consumption via PCA, time to mobilization, and side effects. Patients with contraindications to regional anesthesia or previous lumbar surgery are excluded.
Who should consider this trial
Good fit: Adults 18–70 years old with ASA physical status I–III scheduled for single-level lumbar disc surgery under general anesthesia who can provide informed consent and use a PCA device.
Not a fit: Patients with prior lumbar spine surgery, bleeding disorders or current anticoagulant therapy, allergy to local anesthetics, infection at the injection site, pregnancy or breastfeeding, or inability to use PCA may not benefit or be eligible.
Why it matters
Potential benefit: If one block proves superior, patients could have better pain control with fewer opioids, earlier mobilization, and shorter hospital stays.
How similar studies have performed: Interfascial plane blocks such as TLIP have shown benefit for postoperative spine pain in prior studies, while the Quadro-iliac plane block is a newer variation with limited published evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18-70 years, * Classified as ASA physical status I-III, * Scheduled to undergo single-level lumbar spinal surgery under general anesthesia * Who agree to participate in the study by providing written informed consent Exclusion Criteria: * History of bleeding diathesis or current anticoagulant therapy * Known allergy or hypersensitivity to local anesthetics or opioid medications * Infection at the planned block injection site * Previous lumbar spine surgery * History of gabapentinoid or corticosteroid use within the last 3 weeks * Inability to use a patient-controlled analgesia (PCA) device * Suspected pregnancy, confirmed pregnancy, or breastfeeding * Refusal to undergo the procedure or to participate in the study
Where this trial is running
Samsun
- Samsun University — Samsun, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Hale Kefeli̇ Çeli̇k
- Email: ck_hale@hotmail.com
- Phone: 5057242409
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.