Pulsed radiofrequency therapy for managing neuropathic pain

Prospective Study Upon Pulsed Radiofrequency Therapy on Peripheral Nerves Monitoring Pain, Quality of Life, Patient Satisfaction and Efficacy

Amsterdam UMC, location VUmc · NCT06270940

This study is testing how well pulsed radiofrequency therapy can help people with chronic neuropathic pain feel better and improve their quality of life.

Quick facts

Study typeObservational
Enrollment400 (estimated)
Ages18 Years and up
SexAll
SponsorAmsterdam UMC, location VUmc (other)
Locations1 site (Amsterdam)
Trial IDNCT06270940 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients with chronic peripheral neuropathic pain who are scheduled to receive pulsed radiofrequency (PRF) treatment. The study aims to monitor pain levels, quality of life, patient satisfaction, and the efficacy of the PRF intervention. Patients will be recruited from an outpatient pain clinic, and their data will be collected using a secure electronic data capture system. Informed consent will be obtained from participants, ensuring ethical standards are met throughout the study.

Who should consider this trial

Good fit: Ideal candidates for this study are Dutch-speaking adults aged 18 and older with chronic peripheral neuropathic pain lasting at least six months and a mean pain score of four or higher.

Not a fit: Patients who are unable to complete the required questionnaires or do not meet the inclusion criteria will not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide significant pain relief and improve the quality of life for patients suffering from chronic neuropathic pain.

How similar studies have performed: Previous studies have shown promising results for pulsed radiofrequency treatment in managing chronic peripheral neuropathic pain, indicating that this approach has potential benefits.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients ≥ 18
* Dutch speaking
* Chronic peripheral neuropathic pain lasting ≥ 6 months with mean NRS pain score of ≥ 4
* Patients who are scheduled for an ultrasound guided PRF treatment on a peripheral nerve
* Willing and able to sign consent

Exclusion Criteria:

- Inability to complete the questionnaires

Where this trial is running

Amsterdam

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Neuropathic Pain

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.