Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Pulmonary rehabilitation for patients with advanced lung cancer

Official title: Effect of a Pulmonary Rehabilitation Program on Skeletal Muscle Mass, Pulmonary Function, Inflammatory Response and Overall Survival on Patients Diagnosed With Non-small-cell Advanced Cancer

Run by Instituto Nacional de Cancerologia de Mexico · NCT02978521 · Data updated 2026-11-12

This study is testing whether a special exercise program can help people with advanced lung cancer breathe better, feel stronger, and improve their quality of life.

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Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment94 (estimated)
SponsorInstituto Nacional de Cancerologia de Mexico
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Mexico City, Mexico City)
StatusRecruiting
StartedAugust 5, 2016
Main results expectedDecember 5, 2026
Study endsDecember 12, 2027
Registry record updatedApril 8, 2026
Trial IDNCT02978521 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals diagnosed with advanced non-small cell lung cancer who have a good performance status and are eligible for chemotherapy or tyrosine kinase inhibitors.

Probably not a fit

Patients with symptomatic brain metastasis, uncontrolled pain, or those who regularly engage in moderate to intense physical activity may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effects of a pulmonary rehabilitation program on patients with advanced non-small cell lung cancer. Participants will be randomized into an intervention group, receiving 12 sessions of pulmonary rehabilitation over 4-6 weeks, or a control group, receiving general recommendations for physical activity. The study will assess improvements in pulmonary function, muscle mass, exercise tolerance, inflammatory response, quality of life, and overall survival. Nutritional assessments and interventions will also be provided to both groups as needed.

Why it matters

Potential benefit: If successful, this approach could enhance the quality of life and survival outcomes for patients with advanced lung cancer.

How similar studies have gone: Previous studies have shown positive outcomes with pulmonary rehabilitation in lung cancer patients, suggesting this approach has potential benefits.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Confirmed diagnosis of advanced non-small-cell lung cancer
* Good performance status (ECOG 0-1)
* Life expectancy \>12 weeks
* Eligible to receive treatment with chemotherapy or tyrosinkinase inhibitors
* Recent electrocardiogram without evidence of arrythmia

Exclusion Criteria:

* Symptomatic brain metastasis
* Uncontrolled pain (Visual Analog Scale \>5)
* Uncontrolled hypertension (\>140/100mmHg)
* Practice of regular moderate to intense physical activity at least 3 day/week
* Not residents of Mexico City or unable to attend to therapy sessions

Where it's running

  • Instituto Nacional de Cancerología
    Mexico City, Mexico City, Mexico
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.