Pulmonary rehabilitation for adults on high-flow oxygen

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized interventional study enrolled 70 ICU patients receiving high-flow humidified oxygen and assigned them to pulmonary rehabilitation plus routine care or to routine care alone. The intervention arm received a program of pulmonary rehabilitation while the control arm continued standard medical treatment. Measurements at admission and discharge included bedside diaphragm ultrasound, MRC sum for peripheral muscle strength, a 30‑second sit test, the modified Barthel index, Borg dyspnea score, arterial blood gases, and daily vital sign monitoring; use of noninvasive ventilation, intubation, new complications, and time to first out-of-bed were also recorded. The follow-up period and primary endpoint assessment extended to 28 days.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The age is ≥ 18 years old;
* the hemodynamics is stable;
* 50 \< heart rate \< 120 beats / min ;
* 90 \< systolic blood pressure \< 200mmHg ;
* 55 \< mean arterial pressure \< 120mmHg;
* do not increase the dose of pressor drugs for at least 2 hours;
* intracranial pressure is stable and there are no seizures within 24 hours;
* the respiratory state is stable;
* the patient's finger pulse oxygen saturation ≥ 88%;
* 10 \< respiratory frequency \< 35 beats / min.

Exclusion Criteria:

* Pregnancy;
* acute cardio-cerebrovascular events;
* spinal or limb fractures;
* active bleeding.

Where it's running

• Chinese PLAGH Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: wang, doctor — The First Medical Center of PLA General Hospital
• Study coordinator: kai fei Wang
• Email: zhaoying301301@163.com
• Phone: +861055499330

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.