PRP Injection vs Physiologic Saline for Myofascial Pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares the effects of platelet-rich plasma injections to physiologic saline injections in adults with myofascial pain dysfunction. Eligible participants are women aged 20–40 without chronic illnesses and without recent neck or shoulder surgery. Exclusion criteria include prior muscle-affecting therapies, dental pain as the only cause of pain, pregnancy, allergies, and coagulation disorders. The study aims to determine if PRP offers added benefit over saline in reducing pain and improving function related to myofascial trigger points. Cairo University leads the trial with no listed collaborating sites.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female with age ranging from 20-40 years.
* Suffering from unilateral or bilateral signs and symptoms of myofascial pain dysfunction (MPD), selected patients were systemically free with no chronic diseases.

Exclusion Criteria:

* Patients with history of Malignancy or a history of previous surgery of neck and/or shoulder within the past year of the study.
* Any patient had treatment that can affect the muscles will be excluded, either pharmacological treatment (e.g., opioids, morphine, muscle relaxants or anti-depressants), physiotherapy management or occlusal appliances.
* Patients with pain of dental etiology.
* Pregnant and lactating women and patients with history of allergy or coagulation disorders.

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Abdul-Rahman A Salem, B.Sc
• Email: a.aaskhalil@gmail.com
• Phone: 00201000009344

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Multi-modal imaging to track myofascial neck and shoulder pain

  This project tests whether MRI, surface EMG, and fiber‑optic imaging can track treatment response in adults with chronic myofascial neck or shoulder pain.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07322445

• Using MR elastography to track how manual therapy changes painful lower-back tissues

  This trial will see if a special MRI method (MR elastography) can show tissue changes in adults with chronic lower‑back myofascial pain after Tuina manual therapy compared with usual care.

  Recruiting Mayo Clinic · Rochester, Minnesota and 1 other locations · NCT07278570

• Evaluating PRP injections for knee osteoarthritis treatment

  This study is testing whether platelet-rich plasma (PRP) injections can help people with knee osteoarthritis and related injuries feel better.

  Recruiting Xijing Hospital · Xi'an, Shannxi · NCT06082531

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.