Evaluating PRP injections for knee osteoarthritis treatment
Therapeutic Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis and Periarticular Tissue Injury
This study is testing whether platelet-rich plasma (PRP) injections can help people with knee osteoarthritis and related injuries feel better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 20 Years to 60 Years |
| Sex | All |
| Sponsor | Xijing Hospital Academic / other |
| Drugs / interventions | cart, chemotherapy |
| Locations | 1 site (Xi'an, Shannxi) |
| Trial ID | NCT06082531 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to assess the safety and effectiveness of platelet-rich plasma (PRP) injection therapy for patients suffering from knee osteoarthritis and related soft tissue injuries. Conducted at a single center, the study will involve participants aged 20 to 60 who have been diagnosed with knee osteoarthritis or meniscus injuries. The methodology includes administering PRP injections and monitoring the outcomes to establish a reliable treatment approach for joint injuries.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 20 to 60 with diagnosed knee osteoarthritis or meniscus injuries.
Not a fit: Patients with significant abnormalities in platelet count or function, systemic infections, or those undergoing certain treatments like chemotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a new, effective option for patients with knee osteoarthritis, potentially improving their quality of life.
How similar studies have performed: Other studies have shown promising results with PRP injections for joint injuries, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint. * The preoperative routine tests and examinations revealed no contraindications. * Revised sentence: "Informed consent of the patient Exclusion Criteria: * The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream. * Prolonged usage of anti-inflammatory drugs and systemic corticoid administration. * In injection site or damage to the skin. * Patients with tumors or undergoing radiotherapy and chemotherapy. * Pregnant or breastfeeding women. * Individuals with mental illnesses who are unable to cooperate with follow-up procedures. * Contraindications for MRI、Patients or their families do consent to participate in the study. * Other circumstances that render participation in the study unsuitable.
Where this trial is running
Xi'an, Shannxi
- Xijing Hospital — Xi'an, Shannxi, China (Recruiting)
Study contacts
- Study coordinator: Yanyan Jia
- Email: xiyyllwyh@163.com
- Phone: +862984771794
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.