Protein supplement and exercise program for older adults at risk of sarcopenia
Protein Supplement and Exercise Training for the Treatment of Sarcopenia Risk in Older Adults Who Receive Supportive Home Care: POWER Study
NA · University College Dublin · NCT05688956
This study is testing if a 12-week exercise program combined with a special protein supplement can help older adults at risk of muscle loss feel stronger and improve their overall health while they receive home care.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 70 Years to 100 Years |
| Sex | All |
| Sponsor | University College Dublin (other) |
| Locations | 1 site (Dublin, Leinster) |
| Trial ID | NCT05688956 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of a 12-week resistance exercise program combined with a whey-based protein supplement enriched with leucine and vitamin D for older adults at risk of sarcopenia who receive home care. Participants will be randomly assigned to either the protein supplement group or an exercise-only group, with both groups engaging in an online exercise program delivered via Zoom. The primary outcomes will assess functional and nutritional status, while secondary outcomes will evaluate feasibility, body composition, muscle strength, and quality of life. The exercise program consists of two sessions per week, structured in four phases over the 12 weeks.
Who should consider this trial
Good fit: Ideal candidates are community-dwelling older adults aged 70 and above who require supportive home care and are at risk of sarcopenia.
Not a fit: Patients with cognitive impairment, severe kidney or liver disease, or those regularly undertaking resistance training may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the physical function and nutritional status of older adults at risk of sarcopenia.
How similar studies have performed: Other studies have shown promising results with similar interventions combining nutritional supplementation and exercise for older adults, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Older adults (70+ years) * Requiring supportive homecare * At risk of sarcopenia Exclusion Criteria: * Cognitive impairment * Severe kidney disease (glomerular filtration rate \< 30 mL/min) * Moderate to severe liver disease (Child-Pugh class B or C) * Psychiatric disorder * Receiving treatment or palliative care for cancer * Receiving enteral or parenteral nutrition * Hypersensitivity to any component of ONS * Taking ONS * Allergic to dairy products * Regularly undertaking resistance (strength) training * Advised by GP not to undertake physical activity
Where this trial is running
Dublin, Leinster
- UCD School of Public Health, Physiotherapy and Sports Science — Dublin, Leinster, Ireland (RECRUITING)
Study contacts
- Study coordinator: Catherine Fallon, BSc
- Email: catherine.fallon@ucdconnect.ie
- Phone: +353867240910
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Sarcopenia, Older adults, Home care, Community-dwelling, Oral Nutritional Supplement, Resistance exercise