Proprioceptive training versus sensory re-education to improve balance and walking in people with diabetic peripheral neuropathy
Comparison of Proprioceptive Neuromuscular Training and Sensory Re-education in Patients With Diabetic Peripheral Neuropathy
NA · University of Lahore · NCT07380880
This trial will see if proprioceptive neuromuscular training or sensory re-education helps improve balance and walking in adults with diabetic peripheral neuropathy.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 40 Years to 75 Years |
| Sex | All |
| Sponsor | University of Lahore (other) |
| Locations | 1 site (Lahore, Punjab Province) |
| Trial ID | NCT07380880 on ClinicalTrials.gov |
What this trial studies
This randomized, single-blinded trial will enroll adults with confirmed diabetic peripheral neuropathy and randomly assign them to either a sensory re-education program or a structured proprioceptive neuromuscular training program, alongside baseline conventional care. Both interventions are delivered over six weeks with three supervised sessions per week at a single center in Lahore, Pakistan. Outcome assessors blinded to group allocation will measure balance and gait using the Berg Balance Scale and the Dynamic Gait Index at baseline, mid-intervention (week 3), and at completion. The trial compares within-group and between-group changes to determine which approach more effectively improves postural control and mobility.
Who should consider this trial
Good fit: Adults aged 40–75 with type 1 or type 2 diabetes, confirmed diabetic peripheral neuropathy by standard tools (Michigan Neuropathy Assessment Tool or Toronto Clinical Scoring), and poorly controlled HbA1c (>7% over the past 6 months) who can ambulate are ideal candidates.
Not a fit: People who cannot ambulate independently or have recent musculoskeletal injury, other neurological disorders, renal or liver failure, ischemic heart disease, or other balance-impairing conditions are unlikely to benefit from these interventions in the trial.
Why it matters
Potential benefit: If successful, one approach could offer better improvements in balance and gait, lowering fall risk and improving daily independence for people with DPN.
How similar studies have performed: Previous rehabilitation studies have reported balance and gait improvements with proprioceptive and sensory-based interventions, but direct head-to-head comparisons in diabetic peripheral neuropathy are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Both males and females Diagnosed with Diabetes Mellitus (Type 1 or Type 2) Aged between 40-75 years Presence of diabetic peripheral neuropathy (as confirmed by Michigan Neuropathy Assessment Tool or Toronto Clinical Rating Scale) HbA1c level \> 7% consistently over the last 6 months Exclusion Criteria: Unable to ambulate independently or with assistance Any history of neurological disorders Any history of musculoskeletal disordersin the past 6 months Renal and liver failure History of Ischemic heart disease History of dizziness or balance-impairing conditions
Where this trial is running
Lahore, Punjab Province
- Shadman Medical Center — Lahore, Punjab Province, Pakistan (RECRUITING)
Study contacts
- Principal investigator: Nimra Zaheer, MSPTN — The University of Lahore, Lahore
- Study coordinator: Nimra Zaheer, MSPTN
- Email: nimrazaheer62@gmail.com
- Phone: 03235018078
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Diabetic Peripheral Neuropathy, Proprioceptive Neuromuscular Training, Sensory Re-education, Balance, Gait