Propofol concentration during total intravenous anesthesia and implicit memory

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines how varying propofol concentrations at key moments of anesthesia (loss of responsiveness, maintenance, and return of responsiveness) relate to implicit memory formation. During surgery, patients receive a controlled propofol regimen (TIVA-TCI) with ongoing hypnosis monitoring and a word stream presented to them. Within 24 hours, a psychologist administers memory tests to detect implicit learning, comparing those exposed to the word stream with a control group not exposed to the words. The study records hypnosis level (PSi) and propofol concentrations to explore potential associations. It is conducted at Treviso Regional Hospital with University of Padova as lead sponsor.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* General anaesthesia with TIVA-TCI

Exclusion Criteria:

* ASA \> III
* Benzodiazepines premedication
* Neurological/Psychiatric disease

Where it's running

• Treviso Regional Hospital
  Treviso, Tv, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.