Promoting exercise in seniors to enhance cognitive health
Inspiring Seniors Towards Exercise Promotion to Protect Cognition
This study is testing if adding music to exercise programs helps older adults with memory issues be more active and improve their mental and physical health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Emory University Academic / other |
| Locations | 2 sites (Atlanta, Georgia and 1 other locations) |
| Trial ID | NCT06496425 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effects of beat-accented music stimulation (BMS) on physical activity behaviors and psychological responses in older adults with subjective memory complaints. Participants aged 65 and older will be randomly assigned to an exercise program that includes BMS or one that does not. The intervention consists of supervised strength training and aerobic exercise sessions over six months, with a gradual shift towards independent exercise. The study will assess changes in physical and cognitive functioning, as well as quality of life, resulting from the exercise regimen.
Who should consider this trial
Good fit: Ideal candidates are ambulatory adults aged 65 and older with self-perceived memory complaints who are physically inactive.
Not a fit: Patients with neurological disorders, recent strokes, or those currently undergoing cancer treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance physical activity levels and cognitive health in older adults, potentially delaying the onset of Alzheimer's disease.
How similar studies have performed: Other studies have shown positive outcomes with music-based interventions in promoting physical activity and cognitive health, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults at least 65 years old. * Ambulatory/capable of walking without pain or the use of assisted walking devices. * Able to speak and read English. * Healthy enough to exercise at moderate intensity with or without medical clearance by a primary care physician. * Living in the community for the duration of the study. * Having a reliable means of transportation. * Having a safe place at home or a residential area (at least 6 feet by 6 feet of open space) for unsupervised exercise training. * Being low-active (\< 60 min/week of moderate-intensity aerobic exercise and no strength training for the last 3 months). * Having SCC, defined by the Cognitive Change Index (CCI) ≥ 15. Exclusion Criteria: * Concurrent diagnosis of neurological disorder (e.g., dementia, Parkinson's disease, multiple sclerosis, stroke, etc.). * Known exercise contraindications (uncontrolled hypertension, joint problems, diabetes, metabolic conditions etc.). * Current cancer treatment. * Stroke or neural impairment in the past 6 months. * Hip/knee/spinal fracture or surgery in the past 6 months. * Unable or unwilling to attend intervention classes. * Currently participating in any other physical activity or fitness-related research study. * Use of medication for cognitive impairment. * Regularly drink \> 14 alcoholic beverages a week or current illicit drug use. * Meet the threshold for cognitive impairment. * Meet the threshold for clinical depression. * Uncorrected hearing or visual impairments. * Unable to understand the study procedures. * One of the household members is participating in this study.
Where this trial is running
Atlanta, Georgia and 1 other locations
- Emory University — Atlanta, Georgia, United States (Recruiting)
- UNC Greensboro — Greensboro, North Carolina, United States (Completed)
Study contacts
- Principal investigator: Kyoung Shin Park, PhD — Emory University
- Study coordinator: Study Team
- Email: istep@emory.edu
- Phone: 404-727-8919
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.