Using gait to predict dementia and falls in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the relationship between gait variations and the risk of developing dementia in older adults aged 60 to 85. By monitoring 600 participants over a 25-year period, the study will evaluate cognitive and motor performance through regular assessments, including gait analysis during cognitive tasks. The goal is to identify reliable predictors of dementia progression and mobility decline, which could inform early interventions and improve patient outcomes.

Why it matters

Who can join: the full rules

General Inclusion Criteria:

* Absence of Dementia (DSM IV-TR or DSM V criteria)
* Aged 60-85 years
* Able to walk independently 10 meters without any gait aid (for example: walker, cane);

Exclusion Criteria:

* Unable to understand English;
* Parkinsonism or any neurological disorder with residual motor deficit (e.g.: stroke, epilepsy);
* Musculoskeletal disorder detected by clinical examination which affects gait performance;
* Active osteoarthritis affecting the lower limbs at clinical evaluation
* Use of psychotropics which can affect motor performance (e.g. neuroleptics and benzodiazepines)
* Severe Depression (score \> 12/15 on the Geriatric Depression Scale).

Where it's running

• Gait and Brain Lab, Parkwood Institute
  London, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Dr. Manuel Montero Odasso, M.D. — Director, Gait and Brain Lab
• Study coordinator: Dr. Manuel Montero Odasso, MD, PhD
• Phone: 5196854292

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.