Using gait to predict dementia and falls in older adults
Gait as Predictor of Cognitive Decline, Dementia, and Risk of Falls in MCI. A Cohort Study
This study is trying to see if changes in how older adults walk can help predict their risk of developing dementia and falling.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 60 Years to 85 Years |
| Sex | All |
| Sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Academic / other |
| Locations | 1 site (London, Ontario) |
| Trial ID | NCT03020381 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the relationship between gait variations and the risk of developing dementia in older adults aged 60 to 85. By monitoring 600 participants over a 25-year period, the study will evaluate cognitive and motor performance through regular assessments, including gait analysis during cognitive tasks. The goal is to identify reliable predictors of dementia progression and mobility decline, which could inform early interventions and improve patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are older adults aged 60 to 85 who can walk independently and do not have dementia.
Not a fit: Patients with neurological disorders, severe depression, or those unable to understand English may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a simple and effective method for early detection of dementia risk in older adults.
How similar studies have performed: Other studies have explored gait as a predictor of cognitive decline, suggesting potential success for this approach, though this specific methodology may be novel.
Eligibility criteria
Show full inclusion / exclusion criteria
General Inclusion Criteria: * Absence of Dementia (DSM IV-TR or DSM V criteria) * Aged 60-85 years * Able to walk independently 10 meters without any gait aid (for example: walker, cane); Exclusion Criteria: * Unable to understand English; * Parkinsonism or any neurological disorder with residual motor deficit (e.g.: stroke, epilepsy); * Musculoskeletal disorder detected by clinical examination which affects gait performance; * Active osteoarthritis affecting the lower limbs at clinical evaluation * Use of psychotropics which can affect motor performance (e.g. neuroleptics and benzodiazepines) * Severe Depression (score \> 12/15 on the Geriatric Depression Scale).
Where this trial is running
London, Ontario
- Gait and Brain Lab, Parkwood Institute — London, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Dr. Manuel Montero Odasso, M.D. — Director, Gait and Brain Lab
- Study coordinator: Dr. Manuel Montero Odasso, MD, PhD
- Phone: 5196854292
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.