Program to promote healthy weight gain during pregnancy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This program evaluates the effectiveness of a multi-component lifestyle intervention aimed at promoting appropriate gestational weight gain and preventing gestational diabetes mellitus (GDM) among overweight or obese pregnant women. The intervention combines online and offline health education and utilizes mobile health technology through WeChat to engage participants. A total of 200 overweight or obese singleton pregnant women will be recruited and randomly assigned to either the intervention or control group, with follow-up assessments to measure pregnancy and neonatal outcomes. The study is designed to provide insights into effective strategies for managing weight gain during pregnancy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. At 8-14 weeks of gestation
2. Overweight or obese (pre-pregnancy 40 kg/m2≥BMI≥24 kg/m2) based on BMI recommendations of the Group of China Obesity Task Force of the Chinese Ministry of Health accounting for interracial differences (overweight BMI 24-28 kg/m2 and obese BMI≥28kg/m2)
3. 18-40 years of age
4. Singleton pregnant
5. Skilled at using smartphones and WeChat during pregnancy
6. Attend regular antenatal care and plan delivery at W.F. Maternal and Child Health Hospital or Tongzhou Maternal and Child Health-care Institution of Beijing
7. No contraindications to physical activity according to Physical Activity Readiness Questionnaire (PAR-Q)
8. Willing to be randomized and cooperate with research and regular follow-up visits and sign informed consent.

Exclusion Criteria:

1. Pre-pregnancy hypertension, severe cardiovascular and cerebrovascular diseases, respiratory disease, hepatic and renal disease, malignant tumors, systemic lupus erythematosus, thyroid disease, severe anemia, and other chronic consumptive diseases.
2. Cervical insufficiency (historical painless cervical dilation leading to recurrent second-trimester births in the absence of other causes; dilated cervix on manual or speculum examination, etc.), multiple pregnancy, or continuous vaginal bleeding, etc.
3. Diabetes before pregnancy
4. Special dietary needs (e.g. , vegetarianism)
5. Severe psychiatric disorders (serious mental health disorders including depression, anxiety, bipolar disorders, etc.)
6. Cognitive impairment, visual impairment or hearing impairment
7. History of bariatric surgery or surgical history involving important organs within 3 months
8. Participated in other clinical trials within 6 months

Where it's running

• W.F. Maternal and Child Health Hospital；
  Weifang, Shandong, China Recruiting
• Tongzhou Maternal and Child Health-care Institution
  Beijing, Beijing, China Not yet recruiting

Study contacts

• Principal investigator: Haixue Wang, Doctor — Peking University
• Study coordinator: Haixue Wang, Doctor
• Email: gwwanghaixue@126.com
• Phone: 13041196856

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Gestational weight gain and outcomes after preconception GLP-1 receptor agonist use

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• MR-based performance tests for overweight and obesity

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.