Program to improve bone health in older adults after stroke
Development and Feasibility of a Multi-domain Intervention Program for Post-stroke Bone Health (BOUNCE - Bone Health in Older adUlts' iNtervention Post aCute strokE) in Hospital Pengajar Universiti Putra Malaysia (HPUPM)
NA · Hospital Pengajar Universiti Putra Malaysia · NCT05939531
This study is testing a new program called BOUNCE to see if it can help older adults who have had a stroke improve their bone health and reduce the risk of falls and fractures.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Hospital Pengajar Universiti Putra Malaysia (other) |
| Locations | 1 site (Serdang, Selangor) |
| Trial ID | NCT05939531 on ClinicalTrials.gov |
What this trial studies
This feasibility randomized controlled trial aims to assess the effectiveness of the BOUNCE program, a multi-domain intervention designed to improve bone health in older adults who have experienced an acute stroke. The study will evaluate changes in bone mineral density, incidence of falls, and fractures, as well as the feasibility of implementing the program in clinical settings. It will involve a systematic review, expert consensus development, and a trial comparing the BOUNCE program to standard care. The study will also gather insights on patient and healthcare professional experiences with the intervention.
Who should consider this trial
Good fit: Ideal candidates are older adults aged 50 and above who have been diagnosed with an acute stroke within the last 90 days.
Not a fit: Patients with severe psychological illnesses, chronic kidney disease, or other conditions that impair mobility may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly reduce the risk of bone loss and fractures in older adults recovering from stroke.
How similar studies have performed: While there is limited data on similar multi-domain interventions specifically for post-stroke bone health, related studies have shown promise in addressing bone health in older adults.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 50 years old and older * Neurologist diagnosed acute stroke within 90 days * Has baseline biochemical test upon admission to the ward * Able to undergo DXA scan * Modified Rankin Score of 2 to 3 * Able to walk with or without aids Exclusion Criteria: * Known underlying malignancy * Known major depression or severe psychological illness * Known chronic kidney disease stage 3b (eGFR \<45ml/min/1.73m2) or more * Taken oral glucocorticoids therapy for at least three months * Presence of cognitive impairment (ECAQ \<7) * Presence of coronary artery syndrome or congestive cardiac failure * Presence of an uncontrolled respiratory condition * Underlying malabsorption syndrome * Underlying conditions other than stroke that impairs mobility (eg Severe Osteoarthritis, Parkinson's Disease, Multiple sclerosis) * Known osteoporosis or fragility fracture * Serum phosphate or calcium abnormalities * Discharge to a nursing home or rehabilitation centre * Already a participant in another trial/study
Where this trial is running
Serdang, Selangor
- Hospital Sultan Abdul Aziz Shah — Serdang, Selangor, Malaysia (RECRUITING)
Study contacts
- Study coordinator: Hakimah Mohammad Sallehuddin, MBBS
- Email: drhakimah@upm.edu.my
- Phone: +60397692893
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Bone Loss, Stroke, Geriatrics, Feasibility, Intervention