Prognosis of Aortic Stenosis
Official title: Valvular Aortic Stenosis Prognosis Study: Prospective and Retrospective Follow-up of a Cohort of Patients With Aortic Valve Narrowing
Run by Centre Hospitalier Universitaire, Amiens · NCT03628313 · Data updated 2026-11-12
This study looks at how aortic stenosis affects both patients with and without symptoms to see what risks they face and improve their care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 3450 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens, France) |
| Status | Recruiting |
| Started | September 3, 2015 |
| Main results expected | June 2026 |
| Study ends | June 2026 |
| Registry record updated | June 25, 2026 |
| Trial ID | NCT03628313 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with aortic stenosis who have undergone echocardiographic evaluation.
✕Probably not a fit
Patients who have previously undergone aortic valve surgery or refuse to participate will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the prognosis of patients with aortic stenosis, a common heart valve condition, using transthoracic ultrasound for assessment. It focuses on both asymptomatic and symptomatic patients to better understand the risks associated with this condition. The study will analyze data from patients examined between 2000 and 2014, specifically looking at those with a narrowing of the aortic valve. The aim is to improve prognostic accuracy and patient management in aortic stenosis cases.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of aortic stenosis prognosis, leading to better patient outcomes and management strategies.
How similar studies have gone: Similar studies have shown promise in improving prognostic assessments for aortic stenosis, indicating that this approach is supported by existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Retrospectively, all patients examined from January 1, 2000 to November 2014 will be included in the echocardiography laboratory whose objective examination is a narrowing of the aortic valve (maximum transaortic velocity ≥2.5 m / s). * Aortic stenosis may be known in the past. Exclusion Criteria: * Refusal of the patient to participate in the study. * Patients who have previously had aortic valve surgery before being examined in the echocardiography laboratory. * Patients who can not be contacted or who do not respond will not be included in the database.
Where it's running
-
Chu Amiens-Picardie
Amiens, France, France Recruiting
Study contacts
- Principal investigator: Christophe TRIBOUILLOY, MD, PhD — Chu Amiens
- Study coordinator: Christophe TRIBOUILLOY, MD, PhD
- Email: Tribouilloy.Christophe@chu-amiens.fr
- Phone: 0322087251
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
R21/Matrix-M malaria vaccine: effectiveness and safety in children
This project will try to see if the R21/Matrix‑M vaccine lowers severe and clinical P. falciparum malaria in children and whether vaccinated children have a different risk of death.
-
Effect of Traditional Chinese Medicine on Organ Failure in Critically Ill Patients
This study is testing whether traditional Chinese medicine can help critically ill patients with organ failure in the ICU feel better and recover faster.
-
Examining the effects of bariatric surgery on heart disease and mortality
This study is trying to see if different types of weight-loss surgery can help people with obesity lower their risk of heart disease and live longer compared to those who don't have surgery.
-
Evaluating medical oxygen access and policies
This study looks at how access to medical oxygen works in six countries to see what challenges people face and how to improve it for patients and healthcare providers.
-
Evaluation of a multi-country medical oxygen program
This study is trying to see how medical oxygen is used in hospitals across nine countries to find ways to make it easier for patients, especially children with low oxygen levels, to get the help they need.
-
Registry for patients with chronic hypoparathyroidism
This study looks at how living with chronic hypoparathyroidism affects patients' overall health and quality of life over time, by comparing their experiences with those of similar people without the condition.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.