Probiotics for preventing constipation in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of the probiotic supplement BioKid LR in maintaining normal bowel movements in children aged 6 months to 17 years after discontinuing laxative treatment. Participants will initially take a common laxative, PEG 3350, for 12 weeks, followed by a gradual cessation while continuing with either BioKid LR or a placebo for an additional 12 weeks. The study aims to determine if the probiotic can help prevent the recurrence of constipation without the need for restarting laxatives. Throughout the trial, participants will keep a stool diary to monitor their bowel movements.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 0.5 - 17 years
2. Diagnosis of FC based on Rome IV criteria

Exclusion Criteria:

1. Children with chronic diseases which could cause constipation: Celiac disease, food allergy, Hypothyroidism, Inflammatory Bowel Disease, electrolytes disturbances, Cystic fibrosis, Hirschsprung disease, Neuropathic conditions (Spinal cord trauma, Neurofibromatosis, Tethered cord) or intestinal pseudo-obstruction
2. Prematurity (\<34 weeks)
3. S/P intestinal surgery
4. Immunodeficiency
5. Malignancy
6. Children treated with medications associated with constipation. \*

Where it's running

• Emek Medical Center
  Afula, Israel Recruiting

Study contacts

• Study coordinator: Ferass Abu Hanna, MD
• Email: ferass@Gmail.com
• Phone: 00972546336583

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Gut health follow-along with Peachbiotic in adults

  This single-arm study tests whether Peachbiotic taken daily for 12 weeks helps adults with gut symptoms feel better.

  Recruiting Peach Perfect · Las Vegas, Nevada · NCT07927907

• Prebiotic and Probiotic Combo for Constipation Symptoms

  This study tests whether adding 1-kestose to a probiotic (BBH112) helps adults with constipation-related symptoms see more relief and better quality of life.

  Recruiting Seoul National University Hospital · Seongnam-si, Gyeonggi-do · NCT07923279

• Constipation Prevention Checklist in hip surgery patients

  A simple checklist is used to see if hip surgery patients can stay regular by staying hydrated, eating well, moving early, and using abdominal massage.

  Recruiting Cumhuriyet University · Sivas · NCT07895316

• Abdominal massage training for caregivers to help manage constipation

  Caregivers receive training to use abdominal massage and help their loved ones with constipation in palliative care to see if it improves symptoms and caregiver confidence.

  Recruiting Saglik Bilimleri Universitesi · Istanbul · NCT07886125

• Relationship between body awareness and posture in IBS-C patients compared with healthy people

  This study tests whether people with constipation-predominant IBS have different interoceptive awareness and posture compared with healthy controls.

  Recruiting Saglik Bilimleri Universitesi · Istanbul · NCT07870915

• Gut methane and Parkinson's: measuring if a probiotic helps people with Parkinson's, REM sleep behavior disorder, or cognitive concerns

  This study tests whether a probiotic containing Limosilactobacillus reuteri can help people with Parkinson's disease, those at high risk for PD, and related cognitive issues by potentially improving gut methane levels and overall symptoms.

  Recruiting University of Cambridge · Cambridge, CB2 · NCT07786116

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.