Probiotics for improving pulmonary rehabilitation in COPD patients
Probiotics in the Management of Pulmonary Rehabilitation for COPD: A Randomized Controlled Trial
NA · Fu Jen Catholic University · NCT06717659
This study is testing if taking probiotics can help people with COPD feel better and improve their results during pulmonary rehabilitation.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fu Jen Catholic University (other) |
| Locations | 1 site (New Taipei City) |
| Trial ID | NCT06717659 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of probiotic supplementation on patients with chronic obstructive pulmonary disease (COPD) undergoing pulmonary rehabilitation. It is a one-year, single-center, prospective randomized controlled trial involving 60 participants who will be assigned to either a probiotic intervention group or a conventional rehabilitation group. The study will assess various physiological responses, functional performance, respiratory status, nutritional status, body composition, and biochemical blood parameters, focusing on the anti-inflammatory response. Data will be analyzed statistically to determine the significance of the findings.
Who should consider this trial
Good fit: Ideal candidates include adults diagnosed with pre-COPD or COPD stage I-IV who are currently undergoing pulmonary rehabilitation.
Not a fit: Patients under 18 years old, those with neuromuscular diseases, or individuals experiencing recent respiratory exacerbations may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the nutritional status and lung function of COPD patients, leading to improved rehabilitation outcomes.
How similar studies have performed: Previous studies have shown promising results with probiotic interventions in respiratory conditions, suggesting potential benefits in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Willing to sign a written informed consent form. * Diagnosed with pre-COPD or COPD stage I-IV according to the 2023 GOLD guidelines. * Undergoing pulmonary rehabilitation therapy for more than three months. Exclusion Criteria: * Under 18 years old. * Diagnosed with neuromuscular diseases. * Experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months. * Unable to cooperate with cardiopulmonary exercise testing. * Has other diseases or behavioral restrictions preventing participation in exercise training for over one year. * Assessed by a physician to have severe malnutrition or a significantly low BMI.
Where this trial is running
New Taipei City
- Fu Jen Catholic University Hospital, Fu Jen Catholic University — New Taipei City, Taiwan (RECRUITING)
Study contacts
- Principal investigator: Ke-Yun Chao, PhD — Fu Jen Catholic University
- Study coordinator: Ke-Yun Chao, PhD
- Email: C00152@mail.fjuh.fju.edu.tw
- Phone: +886-905-301-879
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: COPD, Probiotic Intervention, Body Composition Measurement, body composition, inflammation markers, nutritional supplementation, probiotics, chronic obstructive pulmonary disease