Probiotics for improving pulmonary rehabilitation in COPD patients
Official title: Probiotics in the Management of Pulmonary Rehabilitation for COPD: A Randomized Controlled Trial
Run by Fu Jen Catholic University · NCT06717659 · Data updated 2026-11-12
This study is testing if taking probiotics can help people with COPD feel better and improve their results during pulmonary rehabilitation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Fu Jen Catholic University Academic / other |
| Locations | 1 site (New Taipei City) |
| Status | Recruiting |
| Started | December 5, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | February 27, 2026 |
| Trial ID | NCT06717659 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults diagnosed with pre-COPD or COPD stage I-IV who are currently undergoing pulmonary rehabilitation.
✕Probably not a fit
Patients under 18 years old, those with neuromuscular diseases, or individuals experiencing recent respiratory exacerbations may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of probiotic supplementation on patients with chronic obstructive pulmonary disease (COPD) undergoing pulmonary rehabilitation. It is a one-year, single-center, prospective randomized controlled trial involving 60 participants who will be assigned to either a probiotic intervention group or a conventional rehabilitation group. The study will assess various physiological responses, functional performance, respiratory status, nutritional status, body composition, and biochemical blood parameters, focusing on the anti-inflammatory response. Data will be analyzed statistically to determine the significance of the findings.
Why it matters
Potential benefit: If successful, this study could enhance the nutritional status and lung function of COPD patients, leading to improved rehabilitation outcomes.
How similar studies have gone: Previous studies have shown promising results with probiotic interventions in respiratory conditions, suggesting potential benefits in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Willing to sign a written informed consent form. * Diagnosed with pre-COPD or COPD stage I-IV according to the 2023 GOLD guidelines. * Undergoing pulmonary rehabilitation therapy for more than three months. Exclusion Criteria: * Under 18 years old. * Diagnosed with neuromuscular diseases. * Experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months. * Unable to cooperate with cardiopulmonary exercise testing. * Has other diseases or behavioral restrictions preventing participation in exercise training for over one year. * Assessed by a physician to have severe malnutrition or a significantly low BMI.
Where it's running
-
Fu Jen Catholic University Hospital, Fu Jen Catholic University
New Taipei City, Taiwan Recruiting
Study contacts
- Principal investigator: Ke-Yun Chao, PhD — Fu Jen Catholic University
- Study coordinator: Ke-Yun Chao, PhD
- Email: C00152@mail.fjuh.fju.edu.tw
- Phone: +886-905-301-879
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.