Prism Adaptation Therapy for Stroke Rehabilitation
Prism Adaptation Treatment (PAT) for Right Brain Stroke Rehabilitation
NA · VA Office of Research and Development · NCT05983185
This study is testing a new way to help Veterans with spatial neglect after a stroke by using brain scans to find out who would benefit most from a specific therapy that can improve their daily life.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 244 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | VA Office of Research and Development (fed) |
| Locations | 4 sites (West Haven, Connecticut and 3 other locations) |
| Trial ID | NCT05983185 on ClinicalTrials.gov |
What this trial studies
This study focuses on improving rehabilitation for Veterans who experience spatial neglect after a right brain stroke. It aims to develop a brain scanning test that can objectively identify Veterans who are the best candidates for prism adaptation therapy (PAT), a treatment that has shown effectiveness in enhancing functional independence. The research will analyze neurobiological features to create a personalized approach to rehabilitation, addressing the significant treatment gap in cognitive rehabilitation for spatial neglect. By refining the referral process for PAT, the study seeks to improve daily life functions and overall quality of life for affected individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are Veterans who have experienced a first right brain stroke and are 1-4 months post-diagnosis.
Not a fit: Patients with chronic neurological disorders or those who have had a left brain stroke will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance the independence and quality of life for Veterans suffering from spatial neglect after a stroke.
How similar studies have performed: Other studies have shown promise in using similar approaches for cognitive rehabilitation, but this specific biomarker-based method for identifying candidates for PAT is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Has had a first right brain stroke \>18 years of age * 1-4 months post-diagnosis of right brain stroke * Can sit up, see out of both eyes and point to objects (\>20/50 vision in both eyes) * Can give informed consent to participate Exclusion Criteria: * Has been diagnosed with other chronic, disabling neurological disorder (e.g. multiple sclerosis, Alzheimer Disease) * Has had a clinical left brain stroke or has neuroimaging evidence of prior stroke(s) including the presence of more than two lacunes with diameter greater than 15 mm. * Cannot sit up to be tested and receive PAT * Has \<20/50 vision when viewing with both eyes
Where this trial is running
West Haven, Connecticut and 3 other locations
- VA Connecticut Healthcare System West Haven Campus, West Haven, CT — West Haven, Connecticut, United States (RECRUITING)
- Atlanta VA Medical and Rehab Center, Decatur, GA — Decatur, Georgia, United States (RECRUITING)
- VA Central Western Massachusetts Healthcare System, Leeds, MA — Leeds, Massachusetts, United States (RECRUITING)
- Louis Stokes VA Medical Center, Cleveland, OH — Cleveland, Ohio, United States (RECRUITING)
Study contacts
- Principal investigator: Anna M. Barrett, MD — VA Central Western Massachusetts Healthcare System, Leeds, MA
- Study coordinator: Akila Sanjay, BA
- Email: akila.sanjay@va.gov
- Phone: (508) 856-0104
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Spatial Neglect After Right Brain Stroke, spatial neglect, cognition, stroke rehabilitation