Preventive treatment for adjacent segment issues after lumbar fusion surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study focuses on patients undergoing posterior lumbar interbody fusion (PLIF) for degenerative conditions who also have asymptomatic pre-existing spinal canal stenosis at adjacent segments. The research aims to evaluate the effects of limited decompression procedures, such as partial laminotomy and flavectomy, on preventing adjacent segment degeneration and disease. Patients will be monitored through dynamic X-ray and MRI examinations to assess the outcomes of the intervention. The study is designed to provide insights into the management of adjacent segment pathologies following lumbar fusion surgeries.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* A clear diagnosis of lumbar spinal stenosis, and surgical level of L4-S1 (The levels to be operated on were decided by matching the clinical symptomatology with the radiological findings of the spinal levels that needed decompression);
* Patients have asymptomatic pre-existing spinal canal stenosis (cerebrospinal fluid occlusion grade=1) at adjacent segment.
* Failed at least eight weeks conservative treatment;

Exclusion Criteria:

* Unstable factors (slip, rotation, lateral bending, etc.) in adjacent segment L3/4;
* Preoperative sagittal and coronal imbalance of the spine;
* Lumbar infection and/or tumor diseases;
* A previous history of lumbar fusion surgery.

Where it's running

• Peking University Third Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Wei Shi Li, Dr. — Peking University Third Hospital
• Study coordinator: Zhuo Ran Sun, Dr.
• Email: puh3_szr@outlook.com
• Phone: +8618610292513

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.