Preventive Potential of Fluoride Sealants in Adolescent Orthodontic Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study compares two bonding approaches in adolescents starting fixed orthodontic treatment in the upper jaw. Each participant receives a fluoride-releasing adhesive on one side and a standard adhesive on the other, with white spot lesions assessed at baseline and after three months using the Enamel Decalcification Index. The aim is to see if the fluoride sealant can lower the prevalence of white spots during early orthodontic treatment. Participants must be 10–17 years old, have all upper teeth 15–25, and provide consent. Outcomes will inform whether fluoride-releasing bonding agents offer a preventive benefit against demineralization during orthodontic care.

Why it matters

Who can join: the full rules

Inclusion Criteria

* Age between 10 and 17 years
* Initiation of fixed orthodontic treatment in the upper jaw
* Presence of all teeth 15-25
* Written consent from patients and legal guardians

Exclusion Criteria

* Pre-existing white spot lesions
* Active carious lesions
* Structural enamel defects
* Systemic diseases affecting oral health
* Vestibular restorations in the anterior region
* Little Index \> 9

Where it's running

• Sigmund Freud Dental Clinic
  Vienna, Austria Recruiting

Study contacts

• Study coordinator: Linda Schwarz, DMD, PhD
• Email: linda.schwarz@med.sfu.ac.at
• Phone: +43 1 720 19 66

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Remineralizing White Spot Lesions with P11-4: A three-arm trial

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• Hydroxyapatite toothpaste and mouthwash to prevent white spot lesions during orthodontic treatment

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  Recruiting University of Baghdad · Baghdad · NCT07325643

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.