Preventing ventilator-associated pneumonia in the ICU by using evidence-based practices and nurse behavior change
Official title: Effect of Implementing Evidence-based Practice and Nurse's Behavior Change on Quality of Care in Intensive Care Unit: Focus on Ventilator Associated Pneumonia in a Tertiary Hospital in Bangladesh
Run by Hiroshima University · NCT06624540 · Data updated 2026-11-12
This project will try training ICU nurses in evidence-based practices and using recent equipment to see if intubated patients in a Dhaka tertiary hospital have fewer ventilator-associated pneumonias and better outcomes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 272 (estimated) |
| Sponsor | Hiroshima University Academic / other |
| Locations | 2 sites (Dhaka and 1 other locations) |
| Status | Recruiting |
| Started | October 10, 2024 |
| Main results expected | February 28, 2026 |
| Study ends | February 28, 2026 |
| Registry record updated | December 15, 2025 |
| Trial ID | NCT06624540 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are registered Bangladeshi nurses who provide direct ICU care and adult intubated patients (≥18 years) admitted to the participating general ICU with expected stays of at least two days and guardian consent.
✕Probably not a fit
Patients who stay less than two days, are extubated or die within 48 hours, are readmitted to the ICU, or who are not treated in the participating ICU are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This quasi-experimental pre–post study implements simulation-based evidence-based practice (EBP) training for registered ICU nurses and introduces recent technology-based equipment aimed at preventing VAP in a tertiary ICU in Dhaka. The team will measure VAP incidence, device-related pressure ulcers, CLABSI, length of stay, and survival before and after the intervention. Nurses who provide direct patient care will receive behavior-change training and simulation exercises to improve adherence to EBP bundles. Adult intubated patients who remain in the general ICU at least two days will be included and compared to baseline rates.
Why it matters
Potential benefit: If successful, the approach could reduce VAP and other ICU-acquired infections, shorten ICU stays, and improve patient survival in similar hospitals.
How similar studies have gone: Previous work using nurse education and VAP prevention bundles has frequently lowered VAP rates, so the intervention builds on approaches with documented, though variable, success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Study 2: Inclusion criteria: * Who will be a registered nurse in Bangladesh. * Who will agree to participate in this study and the EBP training. Exclusion criteria: * Who will not directly involve patient care in ICU. Study 3: Inclusion Criteria: * Irrespective of age and sex, participant must be 18 years old. * Legal guardian of a patient consents to participation in the study * Intubated patients after admission. Exclusion Criteria: * Who stays less than 2 days at the GICU. * Who dies or is extubated within 2 days after admitted in the GICU. * ICU readmission.
Where it's running
-
Dhaka Medical College Hospital
Dhaka, Bangladesh Recruiting -
Hiroshima University
Hiroshima, Kasumi 1-2-3 Minami-ku, Japan Not yet recruiting
Study contacts
- Study coordinator: Nahida Akhter, Ph. D Fellow
- Email: nahida1789@gmail.com
- Phone: +88-0192-547-8065
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.