Preventing lung complications after laparoscopic liver surgery
Enhanced Perioperative Pulmonary Physiotherapy for Prevention of Pulmonary Complications After Laparoscopic Liver Surgery
NA · Oulu University Hospital · NCT07192575
This will test whether extra breathing exercises and perioperative pulmonary physiotherapy can lower lung complications in adults having elective laparoscopic liver surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 364 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Oulu University Hospital (other) |
| Locations | 5 sites (Kuopio and 4 other locations) |
| Trial ID | NCT07192575 on ClinicalTrials.gov |
What this trial studies
This is a prospective, multicenter, single-blinded randomized controlled trial enrolling about 326 adults scheduled for elective laparoscopic liver surgery. Participants will be randomized to receive enhanced perioperative pulmonary physiotherapy (preoperative counselling, breathing exercises, and peri/postoperative support) or usual care. The main outcome is the incidence of postoperative pulmonary complications using standard EPCO definitions, measured during the hospital stay and early follow-up. The trial is conducted at several university hospitals in Finland with standardized protocols and outcome assessment.
Who should consider this trial
Good fit: Adults scheduled for elective laparoscopic liver surgery who can give informed consent, complete questionnaires, and perform the prescribed breathing exercises are ideal candidates.
Not a fit: People having emergency or planned open liver surgery, those under 18, or those unwilling/unable to consent or perform the exercises are excluded and would not benefit from this protocol.
Why it matters
Potential benefit: If successful, the intervention could reduce postoperative lung complications and related ICU days, shorten hospital stays, and speed recovery after laparoscopic liver surgery.
How similar studies have performed: Previous trials have shown that preoperative respiratory physiotherapy reduces pulmonary complications after open major abdominal and laparoscopic colorectal surgery, but evidence specifically in laparoscopic liver surgery is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria * Patients who undergo elective, laparoscopic surgery of liver * Patients who are able to provide informed written consent * Patients capable of completing questionnaires at the time of consent * Patients compliant in taking in preoperative pulmonary counseling and conducting the exercises Exclusion Criteria: * Age \<18 years * Emergency surgery * Planned open surgery * Unwillingness to participate in the follow up assessment * No informed consent
Where this trial is running
Kuopio and 4 other locations
- Kuopio University Hospital — Kuopio, Finland (NOT_YET_RECRUITING)
- Oulu University Hospital — Oulu, Finland (RECRUITING)
- Tampere University Hospital — Tampere, Finland (NOT_YET_RECRUITING)
- Linköping University Hospital — Linköping, Sweden (NOT_YET_RECRUITING)
- Skåne University Hospital — Lund, Sweden (NOT_YET_RECRUITING)
Study contacts
- Study coordinator: MInna Nortunen, MD PhD
- Email: minna.nortunen@pohde.fi
- Phone: +358453576898
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Liver Surgery, Pulmonary Complications, Laparoscopic Liver Surgery, liver surgery, prehabilitation, pulmonary complications, laparoscopic liver surgery