Preventing lung complications after laparoscopic liver surgery
Official title: Enhanced Perioperative Pulmonary Physiotherapy for Prevention of Pulmonary Complications After Laparoscopic Liver Surgery
Run by Oulu University Hospital · NCT07192575 · Data updated 2026-11-12
This will test whether extra breathing exercises and perioperative pulmonary physiotherapy can lower lung complications in adults having elective laparoscopic liver surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 364 (estimated) |
| Sponsor | Oulu University Hospital Academic / other |
| Locations | 5 sites (Kuopio and 4 other locations) |
| Status | Recruiting |
| Started | September 15, 2024 |
| Main results expected | September 15, 2027 |
| Study ends | October 15, 2027 |
| Registry record updated | September 25, 2025 |
| Trial ID | NCT07192575 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults scheduled for elective laparoscopic liver surgery who can give informed consent, complete questionnaires, and perform the prescribed breathing exercises are ideal candidates.
✕Probably not a fit
People having emergency or planned open liver surgery, those under 18, or those unwilling/unable to consent or perform the exercises are excluded and would not benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, multicenter, single-blinded randomized controlled trial enrolling about 326 adults scheduled for elective laparoscopic liver surgery. Participants will be randomized to receive enhanced perioperative pulmonary physiotherapy (preoperative counselling, breathing exercises, and peri/postoperative support) or usual care. The main outcome is the incidence of postoperative pulmonary complications using standard EPCO definitions, measured during the hospital stay and early follow-up. The trial is conducted at several university hospitals in Finland with standardized protocols and outcome assessment.
Why it matters
Potential benefit: If successful, the intervention could reduce postoperative lung complications and related ICU days, shorten hospital stays, and speed recovery after laparoscopic liver surgery.
How similar studies have gone: Previous trials have shown that preoperative respiratory physiotherapy reduces pulmonary complications after open major abdominal and laparoscopic colorectal surgery, but evidence specifically in laparoscopic liver surgery is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria * Patients who undergo elective, laparoscopic surgery of liver * Patients who are able to provide informed written consent * Patients capable of completing questionnaires at the time of consent * Patients compliant in taking in preoperative pulmonary counseling and conducting the exercises Exclusion Criteria: * Age \<18 years * Emergency surgery * Planned open surgery * Unwillingness to participate in the follow up assessment * No informed consent
Where it's running
-
Oulu University Hospital
Oulu, Finland Recruiting -
Kuopio University Hospital
Kuopio, Finland Not yet recruiting -
Tampere University Hospital
Tampere, Finland Not yet recruiting -
Linköping University Hospital
Linköping, Sweden Not yet recruiting -
Skåne University Hospital
Lund, Sweden Not yet recruiting
Study contacts
- Study coordinator: MInna Nortunen, MD PhD
- Email: minna.nortunen@pohde.fi
- Phone: +358453576898
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.